Protein Alignment Upf1 and CG6204

DIOPT Version :10

• Sequence 1: NP_572767.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: NP_651229.2
• Gene: CG6204 / 42877
• FlyBaseID: FBgn0039165
• Length: 903
• Species: Drosophila melanogaster
• Alignment Length: 757
• Identity: 195/757 - (25%)
• Similarity: 318/757 - (42%)
• Gaps: 187/757 - (24%)

  Fly   221 KQPSE---QGQLRARQISAAQINKLEELWKENIEATF-------------QDLEKPGIDSEPAHV 269
            |.|:|   :|.:..:.:.  .:|.|..|.:|:..|..             .:|::.|:.....|:
  Fly   229 KAPNEEEDEGLVSDKVVK--YVNALRNLLREDFLAPLVEFVQQLRSGTDVDELKQQGLLWSDVHL 291

  Fly   270 LL--RYEDGYQYEKTFGPLVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIAYFTLAKTDSDMK 332
            .|  ::.:..::.     ||.|:.::   .|||   :|....|...:...|:...|.:
  Fly   292 TLNPQFANAQRHS-----LVFLKVQF---TKES---KNAYKTWLNSIKSGTLLCLTTS------- 338

  Fly   333 LMHGDELRLHYVGELYNPWSEIGHVIKVPDNFGDD-VGLELKSSTN-------------APVKCT 383
             :..|:|.|..||     ::|       |:...:| :.:::....|             |||...
  Fly   339 -LAFDDLILASVG-----YTE-------PEKLKEDCLSVQIVKQYNIGNAYNRPLIMFQAPVFFE 390

  Fly   384 SNFTV-DFIWKCTSFDRMTRALCKFAIDRNSVSNFIYSRLLGHGRADSNDEVLFRGPQP------ 441
            ....| :::..|::.        ||.:.|..|              |...|:    |.|
  Fly   391 PYLRVHNYLSTCSTE--------KFPMGRYIV--------------DGQMEI----PPPAYMKPG 429

  Fly   442 -------KLFSAPHLPD---LNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVK---- 492
                   |.|:...||:   ||.||..|.|.||.|..|:||||||||||..|..:|..|::
  Fly   430 VKLSFNMKPFTLDKLPEDLHLNESQKTAFKEALCREFSIIQGPPGTGKTHLSVQLVNSLIQNAKA 494

  Fly   493 LHGGTVLVCAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSELKK 557
            |..|.::|...:|.::|:...||.|...:::|...:||   |..:|...|...|:.......||:
  Fly   495 LGTGPIIVLTYTNNSLDKFLVKISRYTQEILRFGNQSR---DPQISKFNLSTTIKPELVPPRLKR 556

  Fly   558 L---------QQLKDETGELSSAD--EKRYRNLKRAAE--NQLLEAADVI--------------- 594
            :         ::.::..|..::.|  |:.|::...|.|  ||:.|..:.:
  Fly   557 IWWLVNCEYKEKFRNLQGLYANFDGSEESYQDTLAAQEKLNQVAERIETLRMVFQFFLAREKDLL 621

  Fly   595 --CCTCVGAGDGRLSRVKFTSILIDESMQSTEPE---CMVPVVLGAKQLILVGDHCQLGPVVMCK 654
              ..||....:.....::...:|.:|:.:..|..   |:.|   ..:.:||||||.||.|....:
  Fly   622 AMTTTCAARHNFLFRLLQSKCVLFEEAAEIQEAHIVACLTP---HTEHVILVGDHKQLQPFSGSR 683

  Fly   655 KAARAGLSQSLFERLVVLGIRPF-RLEVQYRMHPELSQFPSNFFYEGSLQNGVCA------EDRR 712
            |..:.    ||||||:|.|: || ||.:||||...:|:......|:..|    |:      ||.|
  Fly   684 KVPQI----SLFERLIVAGL-PFSRLNLQYRMRSCISELLVPSIYDELL----CSESVKEYEDIR 739

  Fly   713 LKLDFPWPQPERPMFFLVTQGQEEIAGSGTSFLNRTEAANVEKITTRFL--KAGIKPEQIGIITP 775
            |.        .:.::| |...|.|...|..|..|..||..:.|: |.||  ||..|...|.|::|
  Fly   740 LM--------SKNLYF-VQHNQPEHCMSDMSIGNLYEAGVLAKL-TEFLIQKAQYKHSDIVILSP 794

  Fly   776 YEGQRAYLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLN 840
            |.||...:      :.:|.......:::||||:|||.|.:|:::|.||||....||||....|:.
  Fly   795 YNGQIECI------KNALPQNYRSTVQVASVDSFQGLEANIVLLSLVRSNISGRIGFLRQANRVC 853

  Fly   841 VALTRAKFGIIIVGNPKVLAK--QQLWNHLLNFYKDRKVLVE 880
            |||:||::.:.||||..:|..  .::||.::...|:...:.|
  Fly   854 VALSRARWALYIVGNVTILKDTFPKIWNPIVKRLKENNAIGE 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_572767.1	UPF1_Zn_bind	98..249	CDD:401391	7/30 (23%)
		1B_UPF1-like	302..390	CDD:394815	17/102 (17%)
		TIGR00376	355..880	CDD:273041	165/603 (27%)
		DEXXQc_UPF1	451..684	CDD:350797	79/273 (29%)
CG6204	NP_651229.2	EEXXEc_NFX1	449..708	CDD:350694	78/269 (29%)
		SF1_C_Upf1	710..888	CDD:350195	63/197 (32%)