Protein Alignment Upf1 and CG31368

DIOPT Version :9

• Sequence 1: NP_001285145.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: NP_996198.2
• Gene: CG31368 / 41437
• FlyBaseID: FBgn0051368
• Length: 1486
• Species: Drosophila melanogaster
• Alignment Length: 913
• Identity: 194/913 - (21%)
• Similarity: 336/913 - (36%)
• Gaps: 310/913 - (33%)

  Fly   173 FIPAKADSVVVLLCRQPCAAQNSLKDMNW----DQEQWKPLI--ADRCFLAWLVKQPSEQGQLRA 231
            |:|.     |.|:..:.|..:..| |.|.    |..:.:|.:  .:||:..||     :..|.|
  Fly   598 FVPQ-----VGLVSVRGCEVEGML-DANGRVIEDGPEPRPQLQGENRCYRVWL-----DSNQYR- 650

  Fly   232 RQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEKTFGPLVRLEAEYDQK 296
                                ....||:: |.|           |.|:   :|..|:|      :|
  Fly   651 --------------------LDMDDLQE-GAD-----------DVYE---SFNILMR------RK 674

  Fly   297 LKESATQENIEVRWDVGLNKKTIAYFTLAKTD-------SDMKLMHGDELRLHYVG--------E 346
            .||:..:..:|          ||.:  |..|:       .|:.|.:||....||..        |
  Fly   675 PKENNFKAVLE----------TIRH--LMNTECVVPPWLHDILLGYGDPGAAHYSNMPNQERSLE 727

  Fly   347 LYNPWSEIGHV----------IKVP-DN-------FGDDVGLELKSSTNAPVKCTSNFTVDFIWK 393
            ..:.:.:..|:          .:|| :|       ..:||.::.:|....|.:...
  Fly   728 FNDTFMDYNHLEASFPQYNLKCEVPVENRQPPFRLIFEDVPIQKESDGEDPEEKPE--------- 783

  Fly   394 CTSFDRMTRALCKFAIDRNSVSNFIYSRLLGHGRADSNDEVLFRGP----QPKLFSAPHLPDLNR 454
                :::|:::.        |..:.|..               |||    :||..|....|
  Fly   784 ----EKLTKSIL--------VQPYKYEA---------------RGPYPSDKPKQNSIRFTP---- 817

  Fly   455 SQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLH-GGTVLVCAPSNTAVDQLTEKIHRT 518
            :||.|::..:|..|:|:.||||||||..:..|:..:...| ....|:...||.|::||.|||...
  Fly   818 TQVEAIRAGMQPGLTLVVGPPGTGKTDVAVQIISNIYHNHPNQRTLIVTHSNQALNQLFEKIMAL 882

  Fly   519 NL---KVVRVCAKSREAIDSPVSFLALHNQI-----RNMETNSELKKLQQLKDETGE-------- 567
            ::   .::|: ....||:::...: :.:.::     :.|:..|:::|||:....:|:
  Fly   883 DIDERHLLRL-GHGEEALETEKDY-SRYGRVNYVLAKRMDLLSQVQKLQEALGVSGDNAYTCETA 945

  Fly   568 ----------------------LSSADEKRYR--------------------------------- 577
                                  ...||.::.|
  Fly   946 GYFYLYNVMARWEKFQSQISVHKGEADAEKLRAEFEKEFPFGKFFADAPQPLFKGANYDELMDIA 1010

  Fly   578 --NLK------------RAAE----------NQLLEAADVICCTCVGAGDGRLSRV----KFTSI 614
              |.:            ||.|          ..|::.|.:|..||..|...|...|    ::.:|
  Fly  1011 CSNFRYISDIFNELEEFRAFELLRTGLDRSKYLLVKEAKIIAMTCTHAALKRKELVNLGFRYDNI 1075

  Fly   615 LIDESMQSTEPECMVPVVL--------GAKQLILVGDHCQLGPVVMCKKAA---RAGLSQSLFER 668
            |::||.|..|.|..:|::|        ..|:.|::|||.||.||:  |..|   .:.:.||||.|
  Fly  1076 LMEESAQILEIETFIPLLLQNPLDGLNRLKRWIMIGDHHQLPPVI--KNMAFQKYSNMEQSLFTR 1138

  Fly   669 LVVLGIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCA--EDRRLKLDFPWPQPERPMFFLVT 731
            ||.||:....|:.|                 |..:..:|:  :.|..||:......||..:....
  Fly  1139 LVRLGVPTVDLDGQ-----------------GRARASICSLYKWRYKKLEDLQHIFERDEYKQAN 1186

  Fly   732 QG---------QEEIAGSGTS------FLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRA 781
            .|         .|:..|.|.|      :.|..||..:..:.......|....:|.|:|.|.||:.
  Fly  1187 PGFVHDYQLINVEDFKGVGESEPNPYFYQNLAEAEYIVAVYMYMRLLGYPAAKISILTTYNGQKH 1251

  Fly   782 YLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRA 846
            .:...:..:...:..:....:|.:||.:||::.|.|::|.||:   :.:|.|.|.|||.||::||
  Fly  1252 LIRDVINARCGNNPLIGWPHKITTVDKYQGQQNDYILISLVRT---KAVGHLRDVRRLVVAMSRA 1313

  Fly   847 KFGIIIVGNPKVLAKQQLWNHLLNFYKDRKVLVEGSLNNLKESLIHFQK-PKKLVNSMNIGAHFM 910
            :.|:.:.|      :..|:.:.|...:..|:|.:   ..||.||:...| |...:.|..:.:..:
  Fly  1314 RLGLYVFG------RVSLFKNCLELQQTFKLLTQ---RPLKLSLVPEDKFPTDRLASAAVASQDI 1369

  Fly   911 STI 913
            .|:
  Fly  1370 KTV 1372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_001285145.1	UPF1_Zn_bind	98..249	CDD:286500	16/81 (20%)
		DNA2	122..897	CDD:224037	191/895 (21%)
		Mis12	210..299	CDD:283509	16/90 (18%)
		AAA_19	458..>515	CDD:289986	21/57 (37%)
		AAA_12	661..857	CDD:289832	55/212 (26%)
CG31368	NP_996198.2	Aquarius_N	33..815	CDD:293008	57/317 (18%)
		AAA_11	818..1123	CDD:289831	68/308 (22%)
		AAA_19	821..893	CDD:289986	24/72 (33%)
		DNA2	<1012..1348	CDD:224037	93/366 (25%)
		UvrD_C_2	1131..1321	CDD:304668	54/209 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438987
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10887
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940