Protein Alignment Upf1 and Mov10

DIOPT Version :10

• Sequence 1: NP_572767.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: NP_611185.3
• Gene: Mov10 / 36922
• FlyBaseID: FBgn0034187
• Length: 764
• Species: Drosophila melanogaster
• Alignment Length: 496
• Identity: 146/496 - (29%)
• Similarity: 227/496 - (45%)
• Gaps: 67/496 - (13%)

  Fly   453 NRSQVYAVKHALQRPLS----LIQGPPGTGKTVTSATIVYQL-VKLHGGTVLVCAPSNTAVDQLT 512
            |..|:.||:..:..|.:    ::.||||||||.|....:.|| ::.....:||.|.||:|.|.:.
  Fly   251 NAEQLEAVQRIVAGPSTQGPYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSACDTIA 315

  Fly   513 EKI---HRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSELKKLQQLKDETGELSSADEK 574
            .|:   ..:|:::....|:.:  :..|.     |..||....:...|....:.....:.|:..:.
  Fly   316 LKLCEYIESNIRLQEHFAQQK--LPEPD-----HQLIRVYSRSIYEKGFASVPSLLLKNSNCSKS 373

  Fly   575 RYRNLK--RAAENQLLEAADVICCTCVGAGDGRLSRVK-FTSILIDESMQSTEPECMVPVVLGAK 636
            .|.::|  |..:..::.|.   .||........|.|.. ||.|.|||:..|||||.::. ::|.|
  Fly   374 IYDHIKASRIVKYGIIVAT---LCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEALIG-IMGIK 434

  Fly   637 Q-----LILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVLGI------------RPFRLEVQYR 684
            |     :||.|||.|||.|:...:||..|||:||.|||:....            |..||...||
  Fly   435 QTADCHVILSGDHKQLGAVIKSNRAASLGLSRSLMERLLQSDCYKSDENGNYDRNRQMRLCRNYR 499

  Fly   685 MHPELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPW---PQPERPMFFLVTQGQEEIAGSGTSFLN 746
            .||::.:..:..:|.|.|:....|.|..|..:  |   ..|:.|:.|..|.|......:.||..|
  Fly   500 SHPQIVRLFNELYYNGELKAQAPAMDVNLAAN--WSVLTNPQFPIIFQATHGVTNREQNSTSSYN 562

  Fly   747 RTEAANVEKITTRFLK-AGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLYQEIEIASVDAFQ 810
            ..||..:.....|.:. ..:..|.:||:.||..|...:.:.:|.:|      |..:|:.||:.:|
  Fly   563 NLEAEVICWYVKRLINDRVVGQEDVGIVAPYTAQGKLVTKLLQSKG------YPNVEVGSVETYQ 621

  Fly   811 GREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQLWNHLLNFYKDR 875
            ||||.|||.|.|:|  ...:||:.:|||:||.|:|||..:|:||||..|.....:..::|..|..
  Fly   622 GREKTIIIASLVKS--FTNMGFMCNPRRVNVLLSRAKALLILVGNPVTLRHHSDFKFVINECKKH 684

  Fly   876 --------------KVLVEGSLNNLKESLIHFQKPKKLVNS 902
                          .:|::...:|.:.|.....:..||:.|
  Fly   685 GTYLLKKRDSGQRPHILIKADESNEESSSEPEDEDDKLIPS 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_572767.1	UPF1_Zn_bind	98..249	CDD:401391
		1B_UPF1-like	302..390	CDD:394815
		TIGR00376	355..880	CDD:273041	141/472 (30%)
		DEXXQc_UPF1	451..684	CDD:350797	76/258 (29%)
Mov10	NP_611185.3	DEXXQc_Helz-like	251..499	CDD:350796	76/258 (29%)
		DNA2	<388..684	CDD:440729	105/309 (34%)