Protein Alignment Upf1 and CG6701

DIOPT Version :10

• Sequence 1: NP_572767.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: NP_610920.3
• Gene: CG6701 / 36550
• FlyBaseID: FBgn0033889
• Length: 1333
• Species: Drosophila melanogaster
• Alignment Length: 757
• Identity: 201/757 - (26%)
• Similarity: 309/757 - (40%)
• Gaps: 185/757 - (24%)

  Fly   266 PAHVL--LRYEDGY--------QYEKTFGPLVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIA 320
            |..||  |::||..        ||:           .|.::.:| .||||:           |..
  Fly   377 PIQVLSALKHEDAQMCLASFDNQYQ-----------NYCERGRE-ITQENL-----------TGT 418

  Fly   321 YFTLAKTDSDMKLMH-----GDELRLHYVGELYNPWSEIGHV-IKVPD--NFGDDVGL------- 370
            ..||.:.:...:|.|     ..|:.||..|...:...::|.. :.|.|  :.||||.:
  Fly   419 LRTLLQVEDIERLQHYLSLKQSEMELHQFGRELSVKMQMGTTSMSVEDILSPGDDVLIINEKGNP 483

  Fly   371 ------ELKSSTNAPVKCTSNFTVDFIW------KCTSFDRMTRA---------------LCKFA 408
                  .|:::.|.......:|.....|      ...|.|:..|.               .|:..
  Fly   484 KSAVRKMLENNNNVLELALKDFDSILRWARNVDGMVGSLDKQPRVYFARILGVSTQRVNITCERQ 548

  Fly   409 IDRNSVSNFIYSRL-------------LGHGRADSNDEVLFRGPQPKLFSAPHLPDLNR------ 454
            :..|:....|:..|             |...|......:||.|..|....|..:..||.
  Fly   549 LPDNTTYTLIFRPLRAVMRYQYRALQQLSFTRHSDVQRILFPGEIPNTPLASGVLQLNNKLISTN 613

  Fly   455 -SQVYAVKH-----ALQRPLSLIQGPPGTGKTVTSATIVYQLV----KLHGGTVLVCAPSNTAVD 509
             .|:.||:.     .|:.|. ::.||||||||.|....:|||.    :.|   :||.|.||||.|
  Fly   614 PEQMQAVRQIALSPRLKAPY-IVFGPPGTGKTSTIVEAIYQLYINRPETH---ILVLAGSNTACD 674

  Fly   510 QLTEKIHRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSELKKLQQLKDETGELSSADEK 574
            ::.       |:::|..||:.::...|::.:...|..|.::...:|.                 .
  Fly   675 EVA-------LRLLRAIAKAPQSQPRPLTRIFSANCDRRIDNIDDLL-----------------L 715

  Fly   575 RYRNLKRAAENQLLEAAD---VICCTCVGAG----DGRLSRVKFTSILIDESMQSTEPECMVPVV 632
            .|.|:........::|..   ::.||...||    .|..:...:|.:.:||:..|||.|.::.:.
  Fly   716 EYSNMYTVHFYPAVQAVHQYRIVICTLSLAGKLSTGGFAANNVYTHVFVDEAAASTEAEVLMGIT 780

  Fly   633 LGAK---QLILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVLGIRPFRLE--------VQ---- 682
            ....   .|||.|||.|||||:..::|...||..:|||||  |..:.:::|        ||
  Fly   781 CTLSPTLNLILSGDHKQLGPVLQSQRANEWGLGLTLFERL--LQRKCYQVEEDGSYNASVQTRLI 843

  Fly   683 --YRMHPELSQFPSNFFYEGSLQNG-----VCAEDRRLKLDFPWPQPERPMFFLVTQGQEEIAGS 740
              :|.|||:....:|.:|||.|:..     ||    |....|..|....|:.|....|......|
  Fly   844 RNFRSHPEIVSLYNNMYYEGHLRTEAPMEIVC----RFHNWFYLPNATFPIMFHSVFGTTMNTKS 904

  Fly   741 GTSFLNRTEAANVEKITTRFLKAGIKPEQ-----IGIITPYEGQRAYLVQYMQYQGSLHSRLYQE 800
            ..|..|..|...|.......:..|:..|:     ||||:||:.      ||.:.|..|:.|.:.:
  Fly   905 SVSLCNNKEIDVVMDYVKDLMYFGLNGEKLLQTDIGIISPYKN------QYQRIQEQLNMRNWSQ 963

  Fly   801 IEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQLW 865
            |:..||:.|||:||.:||:|.|||...: :||||:.|||||.|:|....:|::|||:.|::...:
  Fly   964 IDCGSVELFQGKEKHVIIVSFVRSFTPK-LGFLNNERRLNVLLSRPISLLILIGNPRTLSQNSDF 1027

  Fly   866 NHLLNFYKDRKVLV-EGSLNNLKESLIHFQKPKKLVNSMNIG 906
            .|::...::||.|| |..||   |..|  ...|...|::|.|
  Fly  1028 QHIIEMCRNRKTLVGEQYLN---EDFI--TNKKTGANNVNKG 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_572767.1	UPF1_Zn_bind	98..249	CDD:401391
		1B_UPF1-like	302..390	CDD:394815	23/108 (21%)
		TIGR00376	355..880	CDD:273041	169/625 (27%)
		DEXXQc_UPF1	451..684	CDD:350797	74/272 (27%)
CG6701	NP_610920.3	DEXXQc_Helz-like	611..847	CDD:350796	72/265 (27%)
		SF1_C_Upf1	848..1035	CDD:350195	65/197 (33%)