| Sequence 1: | NP_001285145.1 | Gene: | Upf1 / 32153 | FlyBaseID: | FBgn0030354 | Length: | 1180 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002171.2 | Gene: | IGHMBP2 / 3508 | HGNCID: | 5542 | Length: | 993 | Species: | Homo sapiens |
| Alignment Length: | 760 | Identity: | 225/760 - (29%) |
|---|---|---|---|
| Similarity: | 322/760 - (42%) | Gaps: | 147/760 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 289 LEAEYDQKLKESAT-QENIEVRWDVGLNKKTIAYFTLAKTDSDMKLMHGDELRLHYVGELYNPWS 352
Fly 353 EIGHVIKVPDN---FGDDVGLE-------------LKSSTNAPVKCTSNFTVDFIWKCTSFDR-M 400
Fly 401 TRALCKFAID---RNSVSNFIYSRLLGHGRADSNDEVLFRGPQPKLFSAPHLP------DLNRSQ 456
Fly 457 VYAVKHAL-QRPLSLIQGPPGTGKTVTSATIVYQLVKLHGGTVLVCAPSNTAVDQLTEKIHRTNL 520
Fly 521 KVVR------------------VCAKS---------REAIDSPVSFLALHNQIRNMETNSELKKL 558
Fly 559 QQLKDETGELSSADEKRYRNLKRAAENQLLEAADVICCTCVGA-GDGRLSRVK---FTSILIDES 619
Fly 620 MQSTEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAARAGLSQSLFERLV-VLGIRPFR-LEVQ 682
Fly 683 YRMHPELSQFPSNFFYEGSL--QNGVCAEDRRLKLDFP----WPQPERPMFFLVTQG-------Q 734
Fly 735 EEIAGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLYQ 799
Fly 800 EIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQL 864
Fly 865 WNHLLNF------------YKDRKVLVEGSLNNLKESLIHFQKPKKLVNSMNIGAHFMSTIIADA 917
Fly 918 KEVMVPGSIYDRSGGYGQGRQM-VGQSMNG---GQYGGSGGGPYG 958 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Upf1 | NP_001285145.1 | UPF1_Zn_bind | 98..249 | CDD:286500 | |
| DNA2 | 122..897 | CDD:224037 | 210/693 (30%) | ||
| Mis12 | 210..299 | CDD:283509 | 4/9 (44%) | ||
| AAA_19 | 458..>515 | CDD:289986 | 33/57 (58%) | ||
| AAA_12 | 661..857 | CDD:289832 | 71/210 (34%) | ||
| IGHMBP2 | NP_002171.2 | TIGR00376 | 19..641 | CDD:273041 | 201/665 (30%) |
| AAA_19 | 198..256 | CDD:289986 | 33/58 (57%) | ||
| AAA_12 | 418..615 | CDD:289832 | 71/210 (34%) | ||
| SS DNA-binding. /evidence=ECO:0000250 | 638..785 | 22/95 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 651..723 | 19/82 (23%) | |||
| R3H_Smubp-2_like | 726..784 | CDD:100070 | |||
| DUF3628 | <766..850 | CDD:289100 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 782..828 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 841..879 | ||||
| Nuclear localization signal. /evidence=ECO:0000255 | 864..868 | ||||
| zf-AN1 | 897..934 | CDD:279736 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 971..993 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1112 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||