Protein Alignment Upf1 and C41D11.6

DIOPT Version :9

• Sequence 1: NP_001285145.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: NP_491376.1
• Gene: C41D11.6 / 183377
• WormBaseID: WBGene00016565
• Length: 852
• Species: Caenorhabditis elegans
• Alignment Length: 817
• Identity: 154/817 - (18%)
• Similarity: 243/817 - (29%)
• Gaps: 297/817 - (36%)

  Fly    93 KELPPHACKYCGIHDPATVVMCNNCRKWFCNGRGSTSGSHIINHLVRAKHREV--TLHGEGPLGE 155
            :|:|.      .:..||.||                .|....|....|...||  .:..||| |.
 Worm    20 EEMPE------AVEPPANVV----------------EGQAEANRGQAANIGEVYPPVKAEGP-GS 61

  Fly   156 TILECYSCGVRNVFVLGFIPAKADSVVVLLCRQPCAAQN----SLKDMNWDQEQWKPLIADRCFL 216
            .:|...:.|..||.:|                   ..||    :|.:.|.|.||.:..:
 Worm    62 PVLAAGAGGAPNVPIL-------------------PPQNQIPINLNNNNHDNEQERERV------ 101

  Fly   217 AWLVKQPSEQGQLRARQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEK 281
                  |:....||.::...|::.:.::   :|.|..|:.||..|...:..|         .:.:
 Worm   102 ------PNNMRFLRMQRRPWAEMVEEDQ---DNKEHEFEFLEIQGPAPQRHH---------PFRE 148

  Fly   282 TFGPLVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIAYFTLAKTDSDMKLMHGDELRLHYVGE 346
            .:|                 .|.::|.:  :.:.|:..|..||....|         .|.:..||
 Worm   149 HYG-----------------AQPDLEPK--ISVAKRLAAETTLEDVQS---------FRNYTAGE 185

  Fly   347 LYNPWSEIGHVIKVPDNFGDDVGLELKSSTNAPVKCTSNFTVDFIWKCTSFDRMTRALCKFAIDR 411
            ::.|   ..|..|.|               |..|:.:.||..
 Worm   186 IHRP---ALHEDKPP---------------NTMVELSLNFIT----------------------- 209

  Fly   412 NSVSNFIYSRLLGHGRADSNDEVLFRGPQPKLFSAPH-LPDL--NRSQVYAVKH------ALQRP 467
                                          ||.|.|| |..:  |...||.|..      |..||
 Worm   210 ------------------------------KLPSEPHALATIVENNGTVYKVAMVFKEVVANDRP 244

  Fly   468 LSLIQGPPGTGKTVTSATIVYQLVKLH--GGTVLVCAPSNTAVDQLTEKIHRTNLKVVRVCAKSR 530
            ..:..........|||..  |..:|.:  |.|::               ||    |||    |.|
 Worm   245 DLMYMNFTKWSYDVTSRK--YAELKQYYKGDTIM---------------IH----KVV----KRR 284

  Fly   531 EAIDSPVSFLALHNQIRNMETN-----SELKKLQQLKDETGELS----SADEKRYRNLKRAAENQ 586
            :.  :|.||:...:|||||:.:     ||...:|:...|....|    :|..:..:.|......:
 Worm   285 DV--APESFMKTFDQIRNMKAHNYWQVSEFSLVQRKISEPQPFSLVGRAAGGRHSKKLAVCGVTE 347

  Fly   587 LLEAADVICCTCVGAGDGRLSRVKFTSILIDESMQSTEPECMVPVVLGAKQLILVGDHCQLGPVV 651
            ::..::............|...|.||.:||...:              .|.|:....|     :|
 Worm   348 IVTVSEDTFNDNRAPQGYRADAVAFTPVLIPGQL--------------LKSLLPGTPH-----IV 393

  Fly   652 MCKKAARAGLSQSLFERLVVLGIR------PFRLEVQYRM-----------------HPELSQFP 693
            :.::.|....|..|..:::..||.      ||.....|..                 |..||...
 Worm   394 VRRETAAQSKSWDLRPQVINFGIMGARKAYPFLHLPNYMAGRSPNTEDAWRGVRKLGHHGLSAMI 458

  Fly   694 S-------NFFYEGSLQNGVCAEDRRLKLDFPWPQPERPMFFLVTQGQEEIAGSGTSFLNRTEAA 751
            |       .|.||.:||: |...:..:|:.|....|.||:.....:       :||.|...|.|.
 Worm   459 STSNMNQDKFHYETTLQH-VRELEGSMKVSFALQYPGRPVKACNWK-------NGTKFSIETPAG 515

  Fly   752 ------------NVEKITT---RFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLYQEI 801
                        :.:.|||   |.|    :|....:.....|:.|.|::..:   .....|....
 Worm   516 TFVPAAVDHAVQSTDAITTIECRIL----RPADNAVHILAVGEDAVLIKQTK---EADGHLLAAT 573

  Fly   802 EIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRR 838
            .:..||....|.|.:...:.:..........||.|.:
 Worm   574 PVVPVDTVLDRNKGLATFAALNGGPIIASNGLNYPHK 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_001285145.1	UPF1_Zn_bind	98..249	CDD:286500	29/156 (19%)
		DNA2	122..897	CDD:224037	148/788 (19%)
		Mis12	210..299	CDD:283509	12/88 (14%)
		AAA_19	458..>515	CDD:289986	12/64 (19%)
		AAA_12	661..857	CDD:289832	44/223 (20%)
C41D11.6	NP_491376.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810