Protein Alignment Upf1 and eri-7

DIOPT Version :10

• Sequence 1: NP_572767.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: NP_491374.2
• Gene: eri-7 / 172047
• WormBaseID: WBGene00016566
• Length: 625
• Species: Caenorhabditis elegans
• Alignment Length: 519
• Identity: 143/519 - (27%)
• Similarity: 251/519 - (48%)
• Gaps: 81/519 - (15%)

  Fly   449 LPDLNRSQVYAVKHAL--QRPLSLIQGPPGTGKTVTSATIVYQLVKLHGGTVLVCAPSNTAVDQL 511
            :|..|..|..|:|.||  .|.|..||||||||||.|...::.:|:: ....|:|.||:..|:..:
 Worm    63 IPFSNEKQRTAIKMALNENRKLVCIQGPPGTGKTFTLTLLLCRLIQ-QKKQVVVLAPTREALANI 126

  Fly   512 TEKIHRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSE--LKKLQQLKD-----ETGELS 569
            .....:| ||.:.:.......:|:        |:.|::...|:  |...::::|     :.||::
 Worm   127 RMMTKKT-LKRMGIKVHEHALMDT--------NEYRDVINKSDRALMAAEEVRDLRKAFDNGEIT 182

  Fly   570 S--ADEKRYRNLKRAAENQLLEAADVI-----CCTCVGAG--DGRLSRVKFTSIL--IDESMQST 623
            .  .||.|...:.| ..|::  .|:||     ....:||.  |..:...||...|  |||:.|..
 Worm   183 ENVLDEMRQSIINR-VRNEV--GAEVIGNVRVAFATIGASFVDFVMKHKKFDPCLCIIDEAAQVM 244

  Fly   624 EPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVL--GIRPFRLEVQYRMH 686
            |.:.. |.|...|::::.||..||..:|...:|...||..|:.:|::..  ......||.|||.:
 Worm   245 EAQTW-PAVYKMKRIVMAGDPKQLPALVFTDEAKAFGLQNSVMDRILEKKNNFSWIMLENQYRSN 308

  Fly   687 PELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPWPQPER------PMFFLVTQGQEEI-------- 737
            .:::.:.:..||...|:..|...:..|..... |||::      |:..:.|..:.::
 Worm   309 AKIATWSNTCFYHNQLKTDVKCHEYSLHTILN-PQPKKFRNLFDPLVLIDTSLERDVEKRLETYE 372

  Fly   738 -AGSGTSFLNRTEA----ANV--EKIT----TRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQG 791
             |...|:.:|:|:.    ||:  .||.    .|.||.|::|..|.|||||:||.:.:.:.|:..|
 Worm   373 HAVFDTNSINKTKQGFSYANLAEAKIAIGHYQRLLKYGVQPSDIAIITPYKGQTSLVTKLMEEFG 437

  Fly   792 SLHSRL-YQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGN 855
            :..... :.:..|.:||:.||:|.:::|.:.||||.|:.:||:::.|||||.:||||...:.:||
 Worm   438 AETGYTDFVQTTIGTVDSVQGKEYEVVIFTMVRSNPRKTMGFVSELRRLNVVITRAKRHFMFIGN 502

  Fly   856 PKVLAK------QQLWNHLLN----FYKDRKVLVEGSL-----NNL---KESLIHFQKPKKLVN 901
            ..:||:      ::|::...|    |:.:.....:|::     ||.   .||.:::...::::|
 Worm   503 GYLLAESKKDEIRKLYDCFKNAKRRFHPNNAFGEDGNVTDYVSNNFGQDLESFMNYSNDEEMIN 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_572767.1	UPF1_Zn_bind	98..249	CDD:401391
		1B_UPF1-like	302..390	CDD:394815
		TIGR00376	355..880	CDD:273041	137/488 (28%)
		DEXXQc_UPF1	451..684	CDD:350797	71/254 (28%)
eri-7	NP_491374.2	TIGR00376	20..510	CDD:273041	134/461 (29%)