Protein Alignment Upf1 and zgrf1

DIOPT Version :10

• Sequence 1: NP_572767.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: XP_031758647.1
• Gene: zgrf1 / 100327248
• XenbaseID: XB-GENE-6461443
• Length: 1948
• Species: Xenopus tropicalis
• Alignment Length: 770
• Identity: 202/770 - (26%)
• Similarity: 325/770 - (42%)
• Gaps: 139/770 - (18%)

  Fly   211 ADRC-FLAWLVKQPSE---QGQLRARQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLL 271
            :|:| |..||.:....   ||..:.:.:    :..::.:      |:|....|..: .|.:|:::
 Frog  1223 SDQCKFFKWLNETQCSSPVQGHAQPKVV----MGDMKSV------ASFVRSHKVAL-YEESHLMV 1276

  Fly   272 RYEDGYQYEKTFGPLVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIAYFTLAKTDSDMKLMHG 336
            |...|:| .|:||...::                |....|.....||..|..|.:.::.......
 Frog  1277 RKVSGFQ-NKSFGKFKKI----------------INANSDFAGESKTKLYLKLNRKENSSAYSKD 1324

  Fly   337 DELRLHYVGELYNPWSEIGHVIKVPDNFGDDVGLELK-------SSTNAPVKCTSNFTVDFIWKC 394
            |   |..|.:..: :..:...:.....||.....|::       |.:|.|    ||..|..:..|
 Frog  1325 D---LWVVSKTID-FEPVDTFVAFSVFFGPSANNEIEIQPLKGYSPSNWP----SNTLVHAVLVC 1381

  Fly   395 TSFDRMTRALCKFAIDRNSVSNFIYSRLL-------GHGRADSNDEVLFRGPQ--PKLFSAPHLP 450
            .:...:| :|.......|..:..|...||       |..:.::..   |:.|.  .|:.....||
 Frog  1382 NASTELT-SLRNIQEHLNPSTLPIMPHLLKMQSEQEGESKTNTGK---FKPPSLTAKIPQRCELP 1442

  Fly   451 D----------------LNRSQVYAVKH-------------ALQRPLSLIQGPPGTGKTVTSATI 486
            .                ||..|..|:..             |:..|:::|.|..|.||:...:.:
 Frog  1443 SCSFILAKSQEMIEQFRLNEDQATALMQIAQMMTTAAGSYKAVAPPITVIHGVFGAGKSYLLSVV 1507

  Fly   487 VYQLVKL--HGG----------TVLVCAPSNTAVDQ-LTEKIHRTNLKVVRVCAKSREAIDSPVS 538
            |..||:|  .|.          .:|:.:.:|.|||: |...:.....:.|||  .|...|..|:.
 Frog  1508 VLFLVQLFERGNPAEGYEASPWKILISSSTNVAVDRVLLGLLDLGFSQFVRV--GSIRKIAKPIL 1570

  Fly   539 FLALHNQIRNMETNSELKK-LQQLKDETGELSSA-DEKRYRNLKRAAENQLLEAADVICCTCVGA 601
            ..:||....|  .|.::|: |..|||:...:..| ..|.....|......||....|:..||...
 Frog  1571 PFSLHAGSEN--ENEQIKELLALLKDDLTPVEKAYVRKSIEQHKLGTNKALLGQVRVVGATCAAC 1633

  Fly   602 GDGRLSRVKFTSILIDESMQSTEPECMVPVV-LGAKQLILVGDHCQLGPVVM-CKKAARAGLSQS 664
            ....:|.:||..:::||..|.|||..|:||. ...::||||||..||.|.:. .:.|...||.|:
 Frog  1634 PFACMSNLKFPVVVLDECSQMTEPASMLPVARFQCEKLILVGDPKQLSPTIQGSEPAHEKGLEQT 1698

  Fly   665 LFERLVVLGIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPW-PQPERPMFF 728
            ||.||.::|.:...|..|||.||.:....:..||:..|.|||..|||:..||  | |    .:.|
 Frog  1699 LFSRLCLMGHKAIILRTQYRCHPAICSIANELFYDSHLINGVSEEDRKPLLD--WLP----TLCF 1757

  Fly   729 LVTQGQEEIAGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSL 793
            ....|.|::.|: .||.|..||....|:....:.:||:...||:||.|:.|...:...:......
 Frog  1758 YNVNGTEQVEGN-NSFYNMEEANFTVKLIQSLIASGIEGSMIGVITLYKSQMYKIFSLLASSAHC 1821

  Fly   794 HSRLYQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKV 858
            .|...:.:::::||||||.||:|||:||||:.:   :||::..:|:||.|||.|..::|:.|...
 Frog  1822 DSTDIKAVQVSTVDAFQGAEKEIIILSCVRTRQ---VGFIDSEKRMNVGLTRGKRHLLIIANLAC 1883

  Fly   859 LAKQQLWNHLLNFYKDRKVLVEGSLNNLKE----------SLIHFQKPKKLVNSM 903
            |.|.:||.|:::..:.:|       |.||.          .|:.:|: ||:...|
 Frog  1884 LRKNKLWEHVIHHCERQK-------NGLKHVSQWEEKLNAILLRYQE-KKIEEDM 1930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_572767.1	UPF1_Zn_bind	98..249	CDD:401391	7/41 (17%)
		1B_UPF1-like	302..390	CDD:394815	18/94 (19%)
		TIGR00376	355..880	CDD:273041	167/587 (28%)
		DEXXQc_UPF1	451..684	CDD:350797	77/278 (28%)
zgrf1	XP_031758647.1	DUF2439	6..71	CDD:463065
		zf-GRF	1191..1234	CDD:462017	5/10 (50%)
		DNA2	<1521..1900	CDD:440729	128/392 (33%)