DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wisp and tut7

DIOPT Version :9

Sequence 1:	NP_001285144.1	Gene:	wisp / 32152	FlyBaseID:	FBgn0260780	Length:	1373	Species:	Drosophila melanogaster
Sequence 2:	XP_021332039.1	Gene:	tut7 / 562358	ZFINID:	ZDB-GENE-101209-1	Length:	1155	Species:	Danio rerio

Alignment Length:	345	Identity:	87/345 - (25%)
Similarity:	124/345 - (35%)	Gaps:	127/345 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly  1008 FERYRIC--------LVGSTITGFGTDSSDIDMCLLPEQGVHPHQHQYHQHHHFHNEKRTEALII 1064
            ||.:..|        |.||:..|||...||:|:|:..|             .|..........||
Zfish   741 FESFLRCQVPGAKLVLFGSSKNGFGFKQSDLDICMTLE-------------GHDTAMGLDSMAII 792

  Fly  1065 LTLFNAVLKDTEVFQDFNLIEARVPILRFKDISNGIEVDLNFNN------------------CVG 1111
            .:|..|:.|...:.....:..|:|||::|.....|:|.|::..|                  ||.
Zfish   793 ESLAKALRKHHGLRNILPITTAKVPIVKFYHTKTGLEGDISLYNTLCFVEVQINLLDHKQYSCVL 857

  Fly  1112 IKNTYLLQLYAQMDWRTRPLVVIVKLWAQYHDINDAKRMTISSYSLVLMVLHYLQHACVPHVLPC 1176
            :  ...||:|   |.:.:| ||.|..|..|. ..|.|.
Zfish   858 L--LVCLQIY---DGKQKP-VVPVDGWDVYF-FKDLKN--------------------------- 888

  Fly  1177 LHSLYPEKFQLGQQDCLDLDLIEPIEPYQALNTQTLGEHLLGFFKYYS-TFDFRNFAISIRTGGV 1240
            ||..:||                    |:. |.:::||..||..::|: |||||...|.||...
Zfish   889 LHRHWPE--------------------YKK-NRESVGELWLGLLQFYTETFDFRESVICIRRKE- 931

  Fly  1241 LPVSTCRMAKSPKNDVYQW--KELNIEEPFDLSNTARSVYDGPTFERVKAVFL----ISARRL-- 1297
             |:||.:.         ||  |.|.||:|||||:..     |....|..|.|:    |:|||:
Zfish   932 -PLSTFKK---------QWTSKHLAIEDPFDLSHNL-----GAGLSRRMASFIMKAFINARRVFG 981

  Fly  1298 --------DHTLDLATIFRP 1309
                    |::..:...|.|
Zfish   982 SPVRVFPPDYSNKMEYFFDP 1001

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wisp	NP_001285144.1	NT_PAP_TUTase	987..1122	CDD:143392	33/139 (24%)
wisp	NP_001285144.1	PAP_assoc	1211..1272	CDD:281779	26/63 (41%)
tut7	XP_021332039.1	PAP_assoc	150..>499	CDD:332051
		NT_PAP_TUTase	211..323	CDD:143392
		NT_PAP_TUTase	733..838	CDD:143392	29/109 (27%)
		PAP_assoc	902..955	CDD:309089	26/63 (41%)
		AIR1	<1009..1088	CDD:331526
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R202
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940