DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wisp and Tent4b

DIOPT Version :9

Sequence 1:NP_001285144.1 Gene:wisp / 32152 FlyBaseID:FBgn0260780 Length:1373 Species:Drosophila melanogaster
Sequence 2:XP_006255323.1 Gene:Tent4b / 307745 RGDID:1309587 Length:700 Species:Rattus norvegicus


Alignment Length:571 Identity:128/571 - (22%)
Similarity:195/571 - (34%) Gaps:194/571 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   790 SSPCYPASYGSSCGSGTGAGTSPHNNDGNAGALRPASPALSSSSLGSESQ----WSGTSNRSRLG 850
            ||....||.||..|.|:..||:|    ..||..|.....|...::.:|.:    ...|:|     
  Rat    41 SSGASSASGGSGSGPGSPGGTAP----APAGMFRSGERPLGGLAVPAEQRDFLPLETTNN----- 96

  Fly   851 HNGH-------------PSISPTPSALGSAQLSPHLAEMRVQHPLHQQHPPSHASHRPHGQMGGH 902
            :|.|             ||.||.|||..|.         |...||........||...:.:...:
  Rat    97 NNNHHQPAAWARRAAAGPSASPVPSAPSSP---------RPAAPLPASESADPASGSSNKRKRDN 152

  Fly   903 AMSSYVPHRPPPPPHPSISSPNPTPVATG----------AGGPW-------------------YE 938
            ..|:|       ..:.|:..|:....|.|          :|.||                   ||
  Rat   153 KASTY-------GLNYSLLQPSGGRAAGGGRADGGGGVYSGTPWKRRNYNQGVVGLHEEISDFYE 210

  Fly   939 MILP-PDRYLAQARNIEVTVQPEKLICMCKYDNLSAEIWKRFRGAQQTHNKFKLKMRLWRYLYLW 1002
            .:.| |:.   :...:||..:.|.:|         .|:|                          
  Rat   211 YMSPRPEE---EKMRMEVVSRIESVI---------KELW-------------------------- 237

  Fly  1003 MHQPMFERYRICLVGSTITGFGTDSSDIDMCLLPEQGVHPHQHQYHQHHHFHNEKRTEALIILTL 1067
               |..:   :.:.||..||....:||||:.:.                     .:.|.|.:.||
  Rat   238 ---PSAD---VQIFGSFKTGLYLPTSDIDLVVF---------------------GKWENLPLWTL 275

  Fly  1068 FNAVLKDTEVFQDF--NLIEARVPILRFKDISNGIEVDLNFNNCVGIKNTYLLQLYAQMDWRTRP 1130
            ..|:.|.....:|.  .|.:|.|||::..|....::||::||...|::...|::.:.: .:...|
  Rat   276 EEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTK-KYPVLP 339

  Fly  1131 -LVVIVKLWAQYHDINDAKRMTISSYSLVLMVLHYLQ-----HACVPHVLPCLHSLYPEKFQLGQ 1189
             ||:::|.:....|:|:.....|.||||.||.:.:||     .||:|                  
  Rat   340 YLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIP------------------ 386

  Fly  1190 QDCLDLDLIEPIEPYQALNTQTLGEHLLGFFKYYST-FDFRNFAISIRTGGVLPVSTCRMAKSPK 1253
                              || ..|..|:.||:.|.. |::....|.|:.||    |.....:..|
  Rat   387 ------------------NT-NYGVLLIEFFELYGRHFNYLKTGIRIKDGG----SYVAKDEVQK 428

  Fly  1254 N--DVYQWKELNIEEPFDLSN-TARSVYDGPTFERVKAVFLISARRLDHTL 1301
            |  |.|:...|.||:|....| ..||.|..   .:||..|..:...|.|.:
  Rat   429 NMLDGYRPSMLYIEDPLQPGNDVGRSSYGA---MQVKQAFDYAYVVLSHAV 476

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wispNP_001285144.1 NT_PAP_TUTase 987..1122 CDD:143392 28/136 (21%)
PAP_assoc 1211..1272 CDD:281779 19/63 (30%)
Tent4bXP_006255323.1 NT_PAP_TUTase 221..331 CDD:143392 34/171 (20%)
PAP_assoc 389..449 CDD:281779 19/63 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5260
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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