Protein Alignment wisp and TENT2

DIOPT Version :10

• Sequence 1: NP_572766.1
• Gene: wisp / 32152
• FlyBaseID: FBgn0260780
• Length: 1373
• Species: Drosophila melanogaster
• Sequence 2: NP_001336478.1
• Gene: TENT2 / 167153
• HGNCID: 26776
• Length: 509
• Species: Homo sapiens
• Alignment Length: 535
• Identity: 174/535 - (32%)
• Similarity: 252/535 - (47%)
• Gaps: 119/535 - (22%)

  Fly   843 TSNRSRLGHNGHPSISPT---PSALGSAQLSPHLAEM----RVQHPLHQQHPPSHASHRP--HGQ 898
            |.|..:  ||...::|||   ...|..||.:...|::    .:|...:....|...|..|  .|:
Human    13 TPNHQQ--HNNFFTLSPTVYSHQQLIDAQFNFQNADLSRAVSLQQLTYGNVSPIQTSASPLFRGR 75

  Fly   899 ----------MGGHAMSSYVPHRPPPPPHPSISSPNPTPVATGAGGPWYEM-------------- 939
                      :.|.....:.||:.|...:..:      |:   :|...|.|
Human    76 KRLSDEKNLPLDGKRQRFHSPHQEPTVVNQIV------PL---SGERRYSMPPLFHTHYVPDIVR 131

  Fly   940 ILPPDRYLAQARNIEVTVQPEKLICMCKYDNLSAEIWKRFRGAQQTHNKFKLK----MRLWRYLY 1000
            .:||.|.:|.....|:|:...|       |.||.:|.:.|...||..:..|.|    .:|.|.:.
Human   132 CVPPFREIAFLEPREITLPEAK-------DKLSQQILELFETCQQQISDLKKKELCRTQLQREIQ 189

  Fly  1001 LWMHQPMFERYRICLVGSTITGFGTDSSDIDMCLLPEQGVHPHQHQYHQHHHFHNEKRTEALIIL 1065
            |     :|.:.|:.||||::.||||.|||.|:||:.::  .|...|.:|        :|||..||
Human   190 L-----LFPQSRLFLVGSSLNGFGTRSSDGDLCLVVKE--EPCFFQVNQ--------KTEARHIL 239

  Fly  1066 TLFN---------------------------AVLKDTEVFQDFNLIEARVPILRFKDISNGIEVD 1103
            ||.:                           ..|......:...||.|:|||::|:|..:.:|.|
Human   240 TLVHKHFCTRLCKSDMPQVCMSPDVTLLKMPLTLSSAGYIERPQLIRAKVPIVKFRDKVSCVEFD 304

  Fly  1104 LNFNNCVGIKNTYLLQLYAQMDWRTRPLVVIVKLWAQYHDINDAKRMTISSYSLVLMVLHYLQHA 1168
            ||.||.|||:||:||:.||.::.|.||||:::|.||.:|.||||.|.|:||||||||||||||..
Human   305 LNVNNIVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHQINDASRGTLSSYSLVLMVLHYLQTL 369

  Fly  1169 CVPHVLPCLHSLYPEKFQLGQQDCLDLDLIEP----IEPYQALNTQTLGEHLLGFFKYYST-FDF 1228
            ..| :||.|..:|||.|    ...:.|.|:..    :.||.:.|...||:.||||.|||:| ||:
Human   370 PEP-ILPSLQKIYPESF----SPAIQLHLVHQAPCNVPPYLSKNESNLGDLLLGFLKYYATEFDW 429

  Fly  1229 RNFAISIRTGGVLPVSTCRMAKSPKNDVYQW--KELNIEEPFDLSNTARSVYDGPTFERVKAVFL 1291
            .:..||:|....:          |:.|..:|  |.:.:|||||.:||||:|::...|:.:|..||
Human   430 NSQMISVREAKAI----------PRPDGIEWRNKYICVEEPFDGTNTARAVHEKQKFDMIKDQFL 484

  Fly  1292 ISARRLDHTLDLATI 1306
            .|..||.:..||.:|
Human   485 KSWHRLKNKRDLNSI 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wisp	NP_572766.1	TRF4	<1017..>1290	CDD:227585	119/306 (39%)
TENT2	NP_001336478.1	TRF4	154..>493	CDD:227585	140/368 (38%)