Protein Alignment wisp and Tent2

DIOPT Version :9

• Sequence 1: NP_001285144.1
• Gene: wisp / 32152
• FlyBaseID: FBgn0260780
• Length: 1373
• Species: Drosophila melanogaster
• Sequence 2: NP_001348466.1
• Gene: Tent2 / 100715
• MGIID: 2140950
• Length: 484
• Species: Mus musculus
• Alignment Length: 538
• Identity: 179/538 - (33%)
• Similarity: 257/538 - (47%)
• Gaps: 117/538 - (21%)

  Fly   810 TSPHNNDGNAGALRPASPALSSSSLGSESQWS----GTSNRSRLGHNGHPSISP-----TPSALG 865
            |..|....|..||   ||.|.|.....::|::    ..|....|....:.::||     :|...|
Mouse    13 TPTHQQHNNFFAL---SPTLYSHQQLIDAQFNFQNVDLSRAVSLQPLTYGTVSPIQTSTSPLFRG 74

  Fly   866 SAQLSPHLAEMRVQHPLHQQHPPSHASHRPHGQMGGHAMSSYVP------HRPPPPPH----PSI 920
            ..::|...|     .||..:....|:.|:.     ...::..||      :..||..|    |.|
Mouse    75 RKRISDEKA-----FPLDGKRQRFHSPHQE-----PTIINQLVPLSGDRRYSMPPLFHTHYIPDI 129

  Fly   921 SSPNPTPVATGAGGPWYEMILPPDRYLAQARNIEVTVQPEKLICMCKYDNLSAEIWKRFRGAQQT 985
                             ...:||.|.:......|:|:...|       |.||.:|.:.|...||.
Mouse   130 -----------------VRCVPPLREIPLLEPREITLPEAK-------DKLSQQILELFETCQQQ 170

  Fly   986 HNKFKLK----MRLWRYLYLWMHQPMFERYRICLVGSTITGFGTDSSDIDMCLLPEQGVHPHQHQ 1046
            .:..|.|    .:|.|.:.|     :|.:.|:.||||::.|||..|||.|:||:.::  .|...|
Mouse   171 ASDLKKKELCRAQLQREIQL-----LFPQSRLFLVGSSLNGFGARSSDGDLCLVVKE--EPCFFQ 228

  Fly  1047 YHQHHHFHNEKRTEALIILTLFNAVLKDTEVFQDF-----------NLIEARVPILRFKDISNGI 1100
            .:|        :|||..||||         |.:.|           .||.|:|||::|:|..:.:
Mouse   229 VNQ--------KTEARHILTL---------VHKHFCTRLSGYIERPQLIRAKVPIVKFRDKVSCV 276

  Fly  1101 EVDLNFNNCVGIKNTYLLQLYAQMDWRTRPLVVIVKLWAQYHDINDAKRMTISSYSLVLMVLHYL 1165
            |.|||.||.|||:||:||:.||.::.|.||||:::|.||.:||||||.|.|:|||||||||||||
Mouse   277 EFDLNVNNTVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHDINDASRGTLSSYSLVLMVLHYL 341

  Fly  1166 QHACVPHVLPCLHSLYPEKFQLGQQDCLDLDLIE----PIEPYQALNTQTLGEHLLGFFKYYST- 1225
            |....| :||.|..:|||.|....|    |.|:.    .:.||.:.|..:||:.||||.|||:|
Mouse   342 QTLPEP-ILPSLQKIYPESFSTSVQ----LHLVHHAPCNVPPYLSKNESSLGDLLLGFLKYYATE 401

  Fly  1226 FDFRNFAISIRTGGVLPVSTCRMAKSPKNDVYQW--KELNIEEPFDLSNTARSVYDGPTFERVKA 1288
            ||:....||:|....:          |:.|..:|  |.:.:|||||.:||||:|::...|:.:|.
Mouse   402 FDWNTQMISVREAKAI----------PRPDDMEWRNKYICVEEPFDGTNTARAVHEKQKFDMIKD 456

  Fly  1289 VFLISARRLDHTLDLATI 1306
            .||.|.:||.:..||.::
Mouse   457 QFLKSWQRLKNKRDLNSV 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wisp	NP_001285144.1	NT_PAP_TUTase	987..1122	CDD:143392	53/149 (36%)
		PAP_assoc	1211..1272	CDD:281779	24/63 (38%)
Tent2	NP_001348466.1	Nuclear localization signal. /evidence=ECO:0000255	76..92		4/20 (20%)
		TRF4	121..>468	CDD:227585	151/409 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842304
Domainoid	1	1.000	47	1.000	Domainoid score	I11937
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001361
OrthoInspector	1	1.000	-	-		otm42649
orthoMCL	1	0.900	-	-		OOG6_106438
Panther	1	1.100	-	-	LDO	PTHR12271
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R202
SonicParanoid	1	1.000	-	-		X3537
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.730