DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sicily and ndufaf6

DIOPT Version :9

Sequence 1:	NP_001285142.1	Gene:	sicily / 32151	FlyBaseID:	FBgn0030352	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	XP_021322453.1	Gene:	ndufaf6 / 569692	ZFINID:	ZDB-GENE-100112-1	Length:	349	Species:	Danio rerio

Alignment Length:	283	Identity:	115/283 - (40%)
Similarity:	174/283 - (61%)	Gaps:	14/283 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 YGAKHCMSLVEKYDYENYLCTLLLPRELRRAAFALRAFNVEVSR---SVSGHQIEPQIAKMRLKF 112
            :..::|:.:|.|.|||.:||:||||...||:|.||||||||:::   ||| |:   .|..||::|
Zfish    72 HNEQYCIDIVRKKDYEGFLCSLLLPEAARRSALALRAFNVELAQIKDSVS-HK---TIGLMRMQF 132

  Fly   113 WHDSIDKCFEPDSQRSYVEDQPVLRELKHTVGSRKLNKVYLRRLVTARERP-PTHAFESIRELEE 176
            |..:::..:..|...     |||..||...|....|.:.::.|:|:.||:. ...|:.::::||.
Zfish   133 WKSAVEDIYRDDPPA-----QPVSAELWRAVRKHTLTRRWMLRIVSEREKDMEDRAYRNLQDLEA 192

  Fly   177 YTEQTFSSLLLLLLEVGGVRDLNADHAASHLGKAQGIATLLRSIPLAGRQQAPCIPLEVLVLHGV 241
            |.|.|.||||.||||..||::::|||||||:||||||.|.||:.|....::...:|:::.:|||.
Zfish   193 YGENTQSSLLYLLLETLGVKNVHADHAASHIGKAQGILTCLRATPFNSSRRKVYLPMDICMLHGA 257

  Fly   242 SQERIIRSKSDDKGVEDCIFDVASAANTHLKLARQLHDKVPPQVRKIFLSAVATDAYLERLRRAN 306
            |||..||. |.|:.|.|.::|:||.|:.||:.||...:.||......||..|..:.||:|:|:.:
Zfish   258 SQEDFIRG-SRDQNVRDVVYDIASQAHVHLQHARSFAESVPHSAMPAFLQTVVLEDYLQRVRKVD 321

  Fly   307 FLLTHKSCVGRDTLLPARLFWKS 329
            |.:.|.|...|:..||.:|:.:|
Zfish   322 FDVFHPSLQKRNPTLPLQLYLRS 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sicily	NP_001285142.1	SQS_PSY	60..312	CDD:278896	107/255 (42%)
ndufaf6	XP_021322453.1	SQS_PSY	81..327	CDD:306895	107/255 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594933
Domainoid	1	1.000	185	1.000	Domainoid score	I3337
eggNOG	1	0.900	-	-		E1_COG1562
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H43831
Inparanoid	1	1.050	202	1.000	Inparanoid score	I3719
OMA	1	1.010	-	-		QHG63146
OrthoDB	1	1.010	-	-		D488635at33208
OrthoFinder	1	1.000	-	-		FOG0006635
OrthoInspector	1	1.000	-	-		oto39785
orthoMCL	1	0.900	-	-		OOG6_103504
Panther	1	1.100	-	-	LDO	PTHR21181
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3658
SonicParanoid	1	1.000	-	-		X5635
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800