Protein Alignment sicily and FDFT1

DIOPT Version :10

• Sequence 1: NP_572765.1
• Gene: sicily / 32151
• FlyBaseID: FBgn0030352
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_001274679.1
• Gene: FDFT1 / 2222
• HGNCID: 3629
• Length: 476
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 67/342 - (19%)
• Similarity: 109/342 - (31%)
• Gaps: 132/342 - (38%)

  Fly    24 SHAGIHQEAKTNAIPREKKVI-EADKNGYGAKHCMSLVEKYDYENYLCTLLLPRELRRAA----F 83
            ||:..|..:.::..|....|: ..|......|.|...:.:...........|..|:|.|.    .
Human    69 SHSHSHSHSCSSTSPTAVCVVCPQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYL 133

  Fly    84 ALRAFN-VEVSRSVSGHQIEPQIAKMRLKFWHDSIDKCFEPD--------SQRSYVEDQPVL--- 136
            .|||.: :|...::|   :|.::..:     |:.....::||        ..|..:||.|.:
Human   134 VLRALDTLEDDMTIS---VEKKVPLL-----HNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLE 190

  Fly   137 -REL------------------------KHTVGSRKLNK----------VYLRRLVTARERPPTH 166
             |.|                        ||....::.:|          :.|.||.:|.|
Human   191 FRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASE----- 250

  Fly   167 AFESIRELEEYTEQTFSSLLLLLLEVGGVRDLNADHAASHLGKAQGIATLLRSIPLAGRQQAPCI 231
             ||. ..:.|.||:. :|:.|.|.:...:||        :|...||           ||:..|
Human   251 -FED-PLVGEDTERA-NSMGLFLQKTNIIRD--------YLEDQQG-----------GREFWP-- 291

  Fly   232 PLEVLVLHGVSQE---RIIRSKSD-------DKGVEDCIFDVASAANTHLKLARQLHDKVPPQVR 286
                       ||   |.::...|       |..|: |:.::.:.|..|:           |.|
Human   292 -----------QEVWSRYVKKLGDFAKPENIDLAVQ-CLNELITNALHHI-----------PDV- 332

  Fly   287 KIFLSAVATDAYLERLR 303
                     ..||.|||
Human   333 ---------ITYLSRLR 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sicily	NP_572765.1	SQS_PSY	62..311	CDD:425717	59/303 (19%)
FDFT1	NP_001274679.1	squal_synth	97..429	CDD:188157	61/314 (19%)