Protein Alignment HOXB5 and btn

DIOPT Version :10

• Sequence 1: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Sequence 2: NP_732768.1
• Gene: btn / 42664
• FlyBaseID: FBgn0014949
• Length: 158
• Species: Drosophila melanogaster
• Alignment Length: 148
• Identity: 55/148 - (37%)
• Similarity: 79/148 - (53%)
• Gaps: 31/148 - (20%)

Human   123 SASSS-ANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMR-KLH- 184
            ||||| |::.:: |.:..:|..:...|..:|                    |.|..|..| ||.
  Fly    39 SASSSYADYNKL-ETNWCNEANDQWLQNEAP--------------------TGQELPSQRSKLRA 82

Human   185 ISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 249
            ||      ..::.|||:::.|..:||.||.::.||||.||.|||.||.|:|||:|:||||||||.
  Fly    83 IS------SNRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKC 141

Human   250 KKDNKLKSMSLATAGSAF 267
            |: .||:....::|.:.|
  Fly   142 KR-IKLEEQQGSSAKTPF 158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	10/48 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		10/50 (20%)
		Antp-type hexapeptide	176..181		1/4 (25%)
		Homeodomain	195..251	CDD:459649	32/55 (58%)
btn	NP_732768.1	Homeodomain	87..143	CDD:459649	32/55 (58%)