Protein Alignment HOXB5 and lbe

DIOPT Version :10

• Sequence 1: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Sequence 2: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Alignment Length: 181
• Identity: 58/181 - (32%)
• Similarity: 85/181 - (46%)
• Gaps: 22/181 - (12%)

Human   109 GAKP----SASSPSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAP 169
            |..|    |....|:::..:|||...||......:.:.|:..:|..|....:.:.|...|.:...
  Fly   251 GMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKS 315

Human   170 EGQTP--QIFPWMRK----------LHISHDMTGPDGKR-ARTAYTRYQTLELEKEFHFNRYLTR 221
            .|.||  .:|....|          |.|..:...|..|| :|||:|.:|..||||.|.:.:||:.
  Fly   316 NGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSP 380

Human   222 RRRIEIAHALCLSERQIKIWFQNRRMKWKKD-NKLK----SMSLATAGSAF 267
            ..|.|||.:|.||..|:..||||||.|.|:| .:||    |:.:.:|..:|
  Fly   381 ADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSF 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	14/65 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		15/67 (22%)
		Antp-type hexapeptide	176..181		1/4 (25%)
		Homeodomain	195..251	CDD:459649	29/56 (52%)
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	28/55 (51%)