Protein Alignment HOXB5 and lbl

DIOPT Version :10

• Sequence 1: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Sequence 2: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Alignment Length: 234
• Identity: 69/234 - (29%)
• Similarity: 98/234 - (41%)
• Gaps: 50/234 - (21%)

Human    37 PAAMHT---GSYGYNYNGMDLSVNRSSASSSHFGAVGESSRAF---PA-----PAQEPRFRQAAS 90
            |||:||   .:..::|. ..|:.:.......||.|..:..|..   ||     .....|.::::|
  Fly   108 PAALHTFLSPALLHSYE-QRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSSS 171

Human    91 S------CSLSSPESLPCTNGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEEAASQL 149
            |      ||.:..|.:...:.:.....|. .||.:|...||.|:..|.:|          |..||
  Fly   172 SNGSTECCSPTQAEKVEKRSQEDRMEVPK-KSPEEQPKGASKSSGDTPLD----------ALFQL 225

Human   150 SSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKR-ARTAYTRYQTLELEKEF 213
            |:.:.              .|.|.|      ..|:|....:.|..|| :|||:|..|..||||.|
  Fly   226 STKNF--------------DEEQDP------ATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRF 270

Human   214 HFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD 252
            .:.:||:...|.|||..|.||..|:..||||||.|.|:|
  Fly   271 LYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRD 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	23/117 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		22/106 (21%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	29/56 (52%)
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	47/134 (35%)
		Homeodomain	252..308	CDD:459649	28/55 (51%)