Protein Alignment HOXB5 and Scr

DIOPT Version :9

• Sequence 1: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Sequence 2: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 386
• Identity: 122/386 - (31%)
• Similarity: 163/386 - (42%)
• Gaps: 129/386 - (33%)

Human     1 MSSY-FVNSFSGRYPNGPDYQLLNYGSGSSLSG-------------------------------- 32
            |||| ||||.:..||...:.|..:.|:|:|.:|
  Fly     8 MSSYQFVNSLASCYPQQMNPQQNHPGAGNSSAGGSGGGAGGSGGVVPSGGTNGGQGSAGAATPGA 72

Human    33 -SYRDPAAMHT---------------GSYG-------YNYNGMD-----LSVNRSSASSSH---F 66
             .|...||.:|               .:||       .:|..:.     |...:......|   .
  Fly    73 NDYFPAAAAYTPNLYPNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAA 137

Human    67 GAVGESSRAFPA----PAQEPRFRQAASSCSLSSPESLPCTNGDSHGA--------KPSASSPSD 119
            .||....:...|    |.|:.:.:||..||..::.   |.|.|.|.|.        ..||:|.::
  Fly   138 AAVAAQQQQQLAQQQHPQQQQQQQQANISCKYAND---PVTPGGSGGGGVSGSNNNNNSANSNNN 199

Human   120 QATSASSSANFTEID---EASASSEPEEAASQLS----SPSLARAQ-----------------PE 160
            .:.|.:|..:.:..|   :.|.||..|..|..|:    ..|||.|.                 |.
  Fly   200 NSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPG 264

Human   161 PMATSTAAPEG------------------------QTPQIFPWMRKLHISHDMTGPDG--KRART 199
            .:.....:|.|                        ..|||:|||:::|:.......:|  ||.||
  Fly   265 NVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRT 329

Human   200 AYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSL 260
            :|||||||||||||||||||||||||||||||||:|||||||||||||||||::|:.||::
  Fly   330 SYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNI 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	32/139 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		31/155 (20%)
		Antp-type hexapeptide	176..181		3/4 (75%)
		Homeobox	198..251	CDD:395001	50/52 (96%)
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	50/52 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	118	1.000	Domainoid score	I5853
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	1	1.000	-	-		otm40809
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4748
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.800