Protein Alignment HOXB5 and exex

DIOPT Version :10

• Sequence 1: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Sequence 2: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 78/252 - (30%)
• Similarity: 103/252 - (40%)
• Gaps: 80/252 - (31%)

Human    59 SSASSSHFGAVGE--------SSRAFPAPAQEPRFR-QAASSCSLSSPESLP-CTNGDS-HGA-- 110
            :.|::|..|.:.|        .||.:.:|:.:...| ::.:|...|||...| |.:... |||
  Fly   272 AQAAASAAGGISEQEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPGCEDQQQPHGALH 336

Human   111 ----------------KP----SASSPSD----------QATSASSSANFTEIDEASASSEP--- 142
                            ||    |...|.|          |..:...||....:|   .|.:|
  Fly   337 PQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHRPLD---PSGKPIPI 398

Human   143 ----EEAASQLSSPSLARAQ------PEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKRA 197
                ....|||....||||.      ||..|....|..|:|                     :|.
  Fly   399 PMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPHHAILGKT---------------------RRP 442

Human   198 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 254
            |||:|..|.|||||:|..|:||:|.:|.|:|..|.|||.|:||||||||||||:..|
  Fly   443 RTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	37/159 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		34/143 (24%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	35/55 (64%)
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	35/55 (64%)