DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXB5 and unpg

DIOPT Version :9

Sequence 1:NP_002138.1 Gene:HOXB5 / 3215 HGNCID:5116 Length:269 Species:Homo sapiens
Sequence 2:NP_477146.1 Gene:unpg / 35942 FlyBaseID:FBgn0015561 Length:485 Species:Drosophila melanogaster


Alignment Length:249 Identity:78/249 - (31%)
Similarity:98/249 - (39%) Gaps:75/249 - (30%)


- Green bases have known domain annotations that are detailed below.


Human    33 SYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVG--ESSRAFP--APAQEPRFRQAASSCS 93
            |||..|.:....|.::     |||:   |...|..|.|  ...:|.|  |..|||...||.||.:
  Fly   173 SYRRLAELMNQDYVHS-----LSVH---ARLQHMAAAGRMHEDQANPGMAQLQEPTPPQAHSSPA 229

Human    94 LS---SP----------ESLPCTNGDSHGAKPSASSPSDQATSASSSAN--FTEIDEASASSEPE 143
            .|   ||          |...| :|||........||.:.......|.|  :|..|....|.: |
  Fly   230 KSGSHSPMEPALDVGMDEDFEC-SGDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDD-E 292

Human   144 EAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPD-----------GKRA 197
            .|.|:                                   |....|.|.|           .:|.
  Fly   293 GAQSR-----------------------------------HEGGGMGGKDSQGNGSSSNSKSRRR 322

Human   198 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 251
            |||:|..|.||||:|||..:||:...|.:||.:|.|||.|:||||||||.|||:
  Fly   323 RTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXB5NP_002138.1 PRK07003 <67..>171 CDD:235906 30/122 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 77..173 27/112 (24%)
Antp-type hexapeptide 176..181 0/4 (0%)
Homeobox 198..251 CDD:395001 32/52 (62%)
unpgNP_477146.1 Homeobox 324..375 CDD:278475 30/50 (60%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X14
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.900

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