Protein Alignment HOXB5 and cad

DIOPT Version :10

• Sequence 1: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 79/254 - (31%)
• Similarity: 107/254 - (42%)
• Gaps: 50/254 - (19%)

Human    26 SGSSLSGSYRDPAAMHTGSYGY-NYNGMDLSVNRSSASSSHFGAVGESSRAFPAPAQEPRFRQAA 89
            ||||.||          |:.|. ..|..:.|:....|...  |.||.::...|..| .|..:|..
  Fly   123 SGSSSSG----------GAPGAPQLNETNSSIGVGGAGGG--GGVGGATDGGPGSA-PPNHQQHI 174

Human    90 SSCSLSSPESLPCTNGDSHGAKPSASSPSDQAT---SASSSANFTEIDEASASSEPEEAASQLSS 151
            :....|.|.::..:...|.||..|||||.....   ||.::.|....:..::.|......:..|.
  Fly   175 AEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSV 239

Human   152 PSLARAQPEPMATSTAAPEGQTPQIFPWMRK----------------LHISHDMTGPDGK----- 195
            .:..|..|            ..|..|.||:|                |....|:....||
  Fly   240 SNNNRTSP------------SKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKD 292

Human   196 RARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 254
            :.|..||.:|.||||||:..:||:|.||:.|:|..|.|||||:||||||||.|.:|.||
  Fly   293 KYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNK 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	24/106 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		21/98 (21%)
		Antp-type hexapeptide	176..181		2/4 (50%)
		Homeodomain	195..251	CDD:459649	33/60 (55%)
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	32/54 (59%)