Protein Alignment HOXB5 and scro

DIOPT Version :10

• Sequence 1: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Sequence 2: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 210
• Identity: 58/210 - (27%)
• Similarity: 91/210 - (43%)
• Gaps: 57/210 - (27%)

Human    77 PAPAQEPRFRQAASSCSLSSPESLPCTNGDSHGAKPSA-----SSPSDQ-----ATSASSSANFT 131
            |:|     ||..:||.|::||.:|.    .|..|.|.|     .||..|     ..:.|.:.::|
  Fly   139 PSP-----FRSNSSSSSINSPGTLT----TSTMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYT 194

Human   132 EIDEA-----SASSEPEEAASQLSSPSLARAQPEPMATSTAAPEG------------QTPQIFPW 179
            ::..:     |.:::|..|.|:|.|.|         |:.|.:..|            ..|..||.
  Fly   195 DMRNSASWYGSTANDPRFAISRLMSSS---------ASGTMSHMGNMSGLAACSVSDSKPLQFPL 250

Human   180 MRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQN 244
            .::            ::.|..:|:.|..|||:.|...|||:...|..:|..:.|:..|:||||||
  Fly   251 AQR------------RKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQN 303

Human   245 RRMKWKKDNKLKSMS 259
            .|.|.|:..|.|:|:
  Fly   304 HRYKCKRQAKEKAMA 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	28/108 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		29/122 (24%)
		Antp-type hexapeptide	176..181		2/4 (50%)
		Homeodomain	195..251	CDD:459649	22/55 (40%)
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	22/55 (40%)