Protein Alignment CG10353 and ano10a

DIOPT Version :9

• Sequence 1: NP_001245633.1
• Gene: CG10353 / 32148
• FlyBaseID: FBgn0030349
• Length: 1029
• Species: Drosophila melanogaster
• Sequence 2: NP_001025377.1
• Gene: ano10a / 566425
• ZFINID: ZDB-GENE-050913-43
• Length: 646
• Species: Danio rerio
• Alignment Length: 658
• Identity: 161/658 - (24%)
• Similarity: 262/658 - (39%)
• Gaps: 180/658 - (27%)

  Fly   352 IEKLVQDGVYTCAYTLHDKDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQM 416
            :.:|...||....:.||:|:|..||...|....| .:.||||.|:.|||..:.|||.:|.::|..
Zfish   158 VRRLQSKGVLVQYFPLHNKEDLKRLSFSWYKKIK-LSFQPLDDIRSYFGEGLGLYFGFLEYFTFA 221

  Fly   417 LIPISVFGVLCFLYGFITWNSDPISRDICDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNN 481
            |||:::.|:..:|:.                               |.              |.:
Zfish   222 LIPMALIGIPYYLFD-------------------------------WE--------------DYD 241

  Fly   482 MTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQD 546
            ..|:||....:|:.|:||.|||.||.|.:.||..|.....|.||..:...:. ...:.|:.....
Zfish   242 KYVLFAVFNLVWSTVFLEVWKRCSATLAYSWGTLGRKKAFEEPRAGFHGPLG-LNPVTGREEPIY 305

  Fly   547 HTGKR--TILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSM 609
            .:.||  .|....||   |..|..:.|:.:|:::..:...||:   ||.            ||.
Zfish   306 PSSKRHLRIYLVSVP---FVLLCLYLSFYVMMVYFDMEFWAIS---IYH------------ENP- 351

  Fly   610 TFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSL 674
            .|...:|.....||..:||.:::::|...|..||::|..|.::.:...|..|..||.|||.::||
Zfish   352 NFATSVLLFVPSIIYAVVIEIMNLLYRYAAEFLTDWENHRLESSFQNHLVPKVLVFNFVNCFASL 416

  Fly   675 FYIAFLKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCMQLVIIMAGKQAVNAIVEMLIPYLM-- 737
            |||||:....|                        .|...|..::...|.:|.::|..:||.:
Zfish   417 FYIAFVMQDMV------------------------LLRQSLATLLITSQILNQVMEAFLPYWLQR 457

  Fly   738 ----RTFKELSYRHGWYKSHQDQRLVPYNQFTEDYNLLPAENNS---LYVEYLEMVVQFGFITLF 795
                |.:|.:....|      |:.|....|..     |..|.|:   .:.:|||..:.||:::||
Zfish   458 RRNKRVYKRMRRLMG------DKELPLLEQIQ-----LETEMNTYLGTFDDYLEQFLLFGYVSLF 511

  Fly   796 SLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAF 860
            |...|||.:|.:|||:.||..||.||....:||....|.:||||......::.|||.::..:||.
Zfish   512 SCVHPLAAVLVVLNNITEVYSDAFKMCHVFKRPFSEPAANIGVWQLAFETMSIIAVVTNCALIAL 576

  Fly   861 STNLIPKIVYAASMGDPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPH 925
            |               |::..|       |...|.|:
Zfish   577 S---------------PQVKAY-------FPESDAQL---------------------------- 591

  Fly   926 PYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQ 990
                      |||     :|..::::...:.||.:.:|||...:..::.:.:|   |.:...:|:
Zfish   592 ----------ILT-----VVAIEHVLLAFKFILAFVIPDVPKHIQVKLSKLDF---ESLEALKKR 638

  Fly   991 HAMKLVQT 998
            ..:::.:|
Zfish   639 KILEVAET 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10353	NP_001245633.1	Anoct_dimer	183..392	CDD:292796	12/39 (31%)
		Anoctamin	395..977	CDD:282414	142/592 (24%)
ano10a	NP_001025377.1	Anoctamin	200..626	CDD:282414	142/590 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920