Protein Alignment CG10353 and Ano9

DIOPT Version :10

• Sequence 1: NP_727578.3
• Gene: CG10353 / 32148
• FlyBaseID: FBgn0030349
• Length: 1029
• Species: Drosophila melanogaster
• Sequence 2: NP_001419388.1
• Gene: Ano9 / 499287
• RGDID: 1560565
• Length: 753
• Species: Rattus norvegicus
• Alignment Length: 832
• Identity: 272/832 - (32%)
• Similarity: 427/832 - (51%)
• Gaps: 144/832 - (17%)

  Fly   169 PITYSQWKSRTYRRFDDGKRSVDFVLAYNGETQ-LEEHRRKCEIFEANLQREGLQLEHNKVQRVH 232
            |....||               |.||..:.:|| .::|.::.:.|...|:|.|...:..|.|:..
  Rat    28 PEASDQW---------------DCVLVADLQTQKSQKHVQRQQQFLEKLERNGFHFKVLKDQKKV 77

  Fly   233 FIKIHAPAEVLYRYAEILKIKVPLKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNTALFPE 297
            |..|.|.:.|:..|..:|     :||
  Rat    78 FFGIRADSAVIDMYRTLL-----MKP--------------------------------------- 98

  Fly   298 REPRIHLEFSRNYLELYDTEHPNFLDASTRYSIINFILQRQRFVEGE-ETADNLGIEKLVQDGVY 361
            .:||...:             .||..|:||..|:||::..::.:.|| ..||.  .|.||:|||:
  Rat    99 EDPRSRAK-------------QNFNIATTRIRIVNFVVNSKKRLSGELRWADT--FEDLVKDGVF 148

  Fly   362 TCAYTLHDKDDRDRLLKEWANISKWKNL---QPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVF 423
            ...:.|| |.:.| |.:|||   :|:|:   ||:|:|::|||.||||||.|||:||.||:|.:|.
  Rat   149 ETMFLLH-KGEED-LSREWA---QWRNVFQPQPIDKIREYFGEKVALYFTWLGWYTYMLVPAAVV 208

  Fly   424 GVLCFLYGFITWNSDPISRDICDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAF 488
            |::.||.||..::|..||::||..:...|||..|.|..|.||:|.||.:|..:|.||..||:||.
  Rat   209 GLIVFLSGFALFDSSQISKEICSADDIFMCPLGDNSRRYQRLSEMCTFAKLTHLFDNEGTVIFAI 273

  Fly   489 SMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQDHTGKRTI 553
            .||:||.|:||.|||..|..|..|.|                            ||.|...:...
  Rat   274 FMALWATVFLEIWKRKRAREVQSWEL----------------------------YEWDEEEEEMA 310

  Fly   554 LD-PDVPFWSFK-----FLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSMTFK 612
            |: .:.|.:..|     :|.:.....:.:..||:.:.....:::||:...|..|.. .|..:|..
  Rat   311 LELINSPHYELKKHHHSYLSSTIILILSLFMICLMIGMAHLLVVYRVLAAALFSSF-LEQQVTTA 374

  Fly   613 VMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYI 677
            |::   |..::..::|.::..|...:|:||..:|..||.:|.:...|:|.::.||..::|||.||
  Rat   375 VVV---TGAVVHYVIIVIMTKVNKCVALKLCKFEEPRTFSEQESKFTVKFFILQFFAHFSSLIYI 436

  Fly   678 AFLKGKFVGYPAKYNRVLG-FRQEECNPGGCLMELCMQLVIIMAGKQAVNAIVEMLIPYLMRTFK 741
            ||:.|:..|:|.|..|:.| ::.|||:..||:|:|.:|:.|||..||.::..:|.|.|.|....:
  Rat   437 AFILGRINGHPGKSTRLAGLWKLEECHLSGCMMDLFIQMAIIMGLKQTLSNCIEYLYPLLAHKCR 501

  Fly   742 EL-SYRHGWYKSHQDQRLVPYNQFTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLL 805
            .: :||||  :..:|..|.   ::..:|::.|....||:.|::||::|:||.|:|..||||||||
  Rat   502 SVQAYRHG--RKSKDPELA---EWQRNYHMNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLL 561

  Fly   806 ALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVY 870
            ||.:|::|:|||||||:|..||.|..:|:|||.|..::..:..:||.::.|:|||::..||::||
  Rat   562 ALFSNLVEIRLDAIKMVRLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVY 626

  Fly   871 AASMG---------DPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPHP 926
            ....|         |..|.:|:|.:|:||.|||||....:.|.::|  |||||.::||.    |.
  Rat   627 KYHYGPCRKNQTFTDDCLKDYVNHSLSVFYTKDFQDHGRMEGQENV--TVCRYRDYRND----HD 685

  Fly   927 YKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENF 978
            |.....:|.||..||||:::::::...::.|..|.||||...:...:..|.:
  Rat   686 YNLSEQFWFILAIRLAFVILFEHVALCIKLIAAWFVPDVPQSVKNEVLEEKY 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10353	NP_727578.3	Anoct_dimer	183..392	CDD:465044	51/213 (24%)
		Anoctamin	395..976	CDD:461349	215/597 (36%)
Ano9	NP_001419388.1	Anoctamin	180..735	CDD:461349	215/597 (36%)