Protein Alignment CG10353 and Ano10

DIOPT Version :9

• Sequence 1: NP_001245633.1
• Gene: CG10353 / 32148
• FlyBaseID: FBgn0030349
• Length: 1029
• Species: Drosophila melanogaster
• Sequence 2: XP_011241230.1
• Gene: Ano10 / 102566
• MGIID: 2143103
• Length: 670
• Species: Mus musculus
• Alignment Length: 654
• Identity: 162/654 - (24%)
• Similarity: 266/654 - (40%)
• Gaps: 186/654 - (28%)

  Fly   352 IEKLVQDGVYTCAYTLHDKDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQM 416
            :.:|:..|:.|..:.|||.:...:|...|......| .||:|.|:.|||..:||||.:|.::|..
Mouse   158 MRRLLTSGIVTQVFPLHDTEALKKLEDTWYTRFALK-YQPIDSIRSYFGETIALYFGFLEYFTFA 221

  Fly   417 LIPISVFGVLCFLYGFITWNSDPISRDICDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNN 481
            |||:::.|:..:|:   .|.                                          |.:
Mouse   222 LIPMAIIGLPYYLF---VWE------------------------------------------DYD 241

  Fly   482 MTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQD 546
            ..|:||....||:.|.||.|||..|.:.:|||........|.|||.:...:
Mouse   242 KYVIFASFNLIWSTVILEVWKRGCANMTYRWGTLVMKRQFEEPRPGFHGVL-------------- 292

  Fly   547 HTGKRTILDPDVPFWSFKFLPNFTSYSIMVLFICISV-IAIAGIIIYRMAQ---RASHSILGSEN 607
              |..::...:.|.:| .:......|.:.:.|:|:.: .::..::||...:   .:.|...|||
Mouse   293 --GINSVTGREEPLYS-SYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEDWALSLHEDSGSE- 353

  Fly   608 SMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYS 672
             .|..::.:|   .|:..:||.:::.:|...|..||::|..|.::.|...|.:|..||.|:|.::
Mouse   354 -WTSLLLYVP---SIVYAVVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLVLKVLVFNFLNCFA 414

  Fly   673 SLFYIAF-LKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCMQ-LVIIMAGKQAVNAIVEMLIPY 735
            ||||||| ||.                          |:|..| |..::...|.:|.:||.|:||
Mouse   415 SLFYIAFVLKD--------------------------MKLLRQSLATLLITSQILNQVVESLLPY 453

  Fly   736 -LMRTF-KELSYRHGWYKSHQDQRLVPYNQFTEDYNLLPAENNS---LYVEYLEMVVQFGFITLF 795
             |.|.: ..:..:....||..|..|  |.|.     ||..|..:   .:.:|||:.:|||:::||
Mouse   454 WLQRKYCARVKRKVQALKSEVDTTL--YEQV-----LLEKEMGTYLGTFDDYLELFLQFGYVSLF 511

  Fly   796 SLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAF 860
            |..:|||...|:|||..||..||:||.|..:||....:..||||......::.|:|.::..:|..
Mouse   512 SCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFAEPSASIGVWQLAFETMSVISVVTNCALIGM 576

  Fly   861 STNLIPKIVYAASMGDPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPH 925
            |               |::|       |||                              ||..
Mouse   577 S---------------PQVN-------AVF------------------------------PESK- 588

  Fly   926 PYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQ 990
                        |..:..:|..::.:..|:.||.:|:||....:.:::.|         :|:|..
Mouse   589 ------------TDLVLIVVAVEHALLALKFILAFAIPDKPRHIQQKLAR---------LEFESL 632

  Fly   991 HAMK 994
            .|:|
Mouse   633 EALK 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10353	NP_001245633.1	Anoct_dimer	183..392	CDD:292796	10/39 (26%)
		Anoctamin	395..977	CDD:282414	146/592 (25%)
Ano10	XP_011241230.1	Anoctamin	200..626	CDD:367984	145/590 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920