Protein Alignment CG10353 and LOC100490855

DIOPT Version :10

• Sequence 1: NP_727578.3
• Gene: CG10353 / 32148
• FlyBaseID: FBgn0030349
• Length: 1029
• Species: Drosophila melanogaster
• Sequence 2: XP_031756610.1
• Gene: LOC100490855 / 100490855
• XenbaseID: XB-GENE-29080411
• Length: 798
• Species: Xenopus tropicalis
• Alignment Length: 867
• Identity: 265/867 - (30%)
• Similarity: 433/867 - (49%)
• Gaps: 162/867 - (18%)

  Fly   191 DFVLAYNGETQLEEHRRKCEIFEANLQREGLQLEHNKVQRVHFIKIHAPAEVLYRYAEILKIKVP 255
            |:||.....:......:|.:.:.:.|.::|.:.:..:..:|.|..:.||.::.::|..:|.
 Frog    44 DYVLVCKPTSTDSPEEQKRQHYISVLLKKGFKTKKVRDGKVTFYGVRAPTDIFHKYVRLLH---- 104

  Fly   256 LKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNTALFPEREPRIHLEFSRNYLELYDTEHPN 320
             .|..|...|                                                   |.|
 Frog   105 -NPDKGHTSI---------------------------------------------------ESP- 116

  Fly   321 FLDASTRYSIINFILQRQRFV-EGEETADNLGIEKLVQDGVYTCAYTLHDKDD--RDRLLKEWAN 382
             :..::|..|::|||.....: .|:|..    ::.|::..|:..|:.||.:.|  |:.|.|:||
 Frog   117 -VSPTSRIRIVHFILHNTAILFRGKEEK----LQDLIKTQVFEAAFPLHTRKDQTREGLKKKWA- 175

  Fly   383 ISKWKNL---QPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDI 444
              :|:::   ||:::|:.|:|.||||||||||:||.||:..:|.|::.|.|||:.:::..||::|
 Frog   176 --RWRDIIYVQPIEEIRAYYGEKVALYFAWLGWYTIMLLYAAVVGLIVFFYGFVHFDNSQISQEI 238

  Fly   445 CDDNGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLV 509
            |..|.|:|||.||::|.||.|::|||.:|..:|.||..||.||..||:||.|:||.|||..|..|
 Frog   239 CTANNTLMCPLCDQNCPYWPLSDTCTYAKVTHLFDNEGTVFFAMFMAVWATVFLELWKRARANTV 303

  Fly   510 HRWGLTGFTHHVEHPRPQYLARISRTKKLAGKAYEQDHTGKRTILDPDVPFWSFKFLPNFTSYSI 574
            ..|.|..:....|.                 .|.|..:..:.||...:..:|.          |:
 Frog   304 SGWNLYNWDEDEEE-----------------LALELINDPECTIKKHEHSYWR----------SM 341

  Fly   575 MVLFICISVIAI-----AGIIIYRMA-----QRASHSILGSENSMTFKVMILPMTAGIIDLIVIS 629
            .||.....|||:     ..::|||:.     .|:|...| .|::.|..|    |:..::..:.|.
 Frog   342 AVLLGAAVVIAVLIGIAQALVIYRVVVTVSFMRSSWEFL-REHANTAAV----MSGAVLHYLTIV 401

  Fly   630 LLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRV 694
            ::..|...:|..|.|.|..||.||.:.|.|.|.:.||||.::|||||:||..|:..|||..|.|:
 Frog   402 IMTKVNRVIAGYLCNLEKPRTFTERENSFTTKVFTFQFVTHFSSLFYVAFFLGRINGYPGNYVRI 466

  Fly   695 LG-FRQEECNPGGCLMELCMQLVIIMAGKQAVNAIVEMLIPYLMRTFKELSYRHGWYKSHQDQRL 758
            .| :|.|||:|.||:.:|.:|:.:||..||.::..||.|.||       .||:   ::..:|:|.
 Frog   467 AGQWRLEECHPSGCITDLFIQMCVIMVLKQTLSNCVEYLSPY-------FSYK---WRLMKDRRC 521

  Fly   759 VPYNQ----------FTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIE 813
            ..:.:          :..:|.|......||:.|:||||:|:.|.|:|..||||||:||.||||:|
 Frog   522 RVHGEDGSEDSAAECWRTNYRLGAVHVFSLFDEFLEMVIQYSFTTIFVAAFPLAPVLAFLNNVLE 586

  Fly   814 VRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVY-----AAS 873
            :|||||||.|..||.|..:|.|||:|..::..|..:||.::.::||.:::.||:::|     ..:
 Frog   587 IRLDAIKMTRLQRRFVPRKANDIGIWLQVLEAVGVLAVITNGLVIAVTSDFIPRLIYLYVYGPCA 651

  Fly   874 MGDPE----LNNYLNFTLAVFNTKDFQVQPLLGGSQHVNETVCRYTEFRNSPEDPHPYKRPMIYW 934
            .|..|    |:.|::.:|:||.||||:....:..|.:.|.|.|||.::|::.:    |.....:|
 Frog   652 NGTTEGINCLSGYVDSSLSVFYTKDFEDLTQVSRSLYTNVTECRYRDYRSAAD----YSFSTQFW 712

  Fly   935 KILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTE 999
            .|...||.|:::::::...::.:..|.|||:..|:      ||:.|     :.:|||.::    |
 Frog   713 HIFAARLGFLIVFEHVAVCIKFVAAWFVPDIPQRV------ENYNL-----DMKKQHLLE----E 762

  Fly  1000 LNGQQKSEGELRQRNNETVIRN 1021
            |:...:...|..:..:....|:
 Frog   763 LSMMPEESDEYHKEGSPNSYRD 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10353	NP_727578.3	Anoct_dimer	183..392	CDD:465044	37/206 (18%)
		Anoctamin	395..976	CDD:461349	217/610 (36%)
LOC100490855	XP_031756610.1	Anoct_dimer	44..186	CDD:465044	37/206 (18%)
		Anoctamin	189..757	CDD:461349	220/624 (35%)