Protein Alignment CG10353 and ano10

DIOPT Version :9

• Sequence 1: NP_001245633.1
• Gene: CG10353 / 32148
• FlyBaseID: FBgn0030349
• Length: 1029
• Species: Drosophila melanogaster
• Sequence 2: XP_002937896.1
• Gene: ano10 / 100487513
• XenbaseID: XB-GENE-955754
• Length: 651
• Species: Xenopus tropicalis
• Alignment Length: 763
• Identity: 190/763 - (24%)
• Similarity: 297/763 - (38%)
• Gaps: 219/763 - (28%)

  Fly   267 AESAHEFKTCFSRMCKSLFSSVQLNTALFPEREPRIHLEFSRNYLELYDTEHPNFLDASTRYSII 331
            |||....|.|.....|....|        ..:|.:...|...|:|.:.|.::      ..:|.:.
 Frog    78 AESVGMVKECIDGSMKPFIYS--------NRKEYKDWTEDGENFLSMADCQY------IIKYELD 128

  Fly   332 NFILQRQRFVEGEETA----DNLGIEKLVQDGVYTCAYTLHDKDDRDRLLKEWANISKWKNLQPL 392
            |...|.::.:.|...:    ......:|...|:....:.||||::..||..:|....|.. .||:
 Frog   129 NLRAQDEKNIPGYPNSKLYPGKSIFRRLKTSGIMIQVFPLHDKEELKRLRHQWYLRIKLA-FQPI 192

  Fly   393 DQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDDNGTIMCPQCD 457
            |||:.|||..:.||||:|.::|..|||:::.|:   .|.|..|.
 Frog   193 DQIQHYFGDTLGLYFAFLEYFTMALIPMALIGI---PYYFFDWE--------------------- 233

  Fly   458 RSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVE 522
                                 |.:..|:||....:|:.|.||.|||.|:.:.:|||........|
 Frog   234 ---------------------DYDKYVIFATFNLVWSTVILEVWKRLSSAMTYRWGSLIMKRKFE 277

  Fly   523 HPRPQYLARISRTKKLAGKAYEQDHTGKRTILDPDVPFWSFKFLPNFTSYSIMVLFICISV-IAI 586
            .|||.:          .|.......||::.      |.:| .|......|.:.|.|:|:.: :||
 Frog   278 EPRPGF----------HGVLGINPVTGRKE------PIYS-SFKRQLRIYLVSVPFVCVCLYLAI 325

  Fly   587 AGIIIYRMAQR---ASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYC 648
            ..::||...:.   |.|    .|...||..::| ....||..:||.:|:.:|...|..||::|..
 Frog   326 YVMMIYFDLEHWALAYH----QEQQSTFSNLLL-YVPSIIYAVVIEILNRIYKIAAEFLTSWENH 385

  Fly   649 RTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCM 713
            |.::.|...|.:|..||..||.::|||||||:.                         |.|:|..
 Frog   386 RLESSYQNHLVLKVLVFNIVNCFASLFYIAFVM-------------------------CDMKLLR 425

  Fly   714 Q-LVIIMAGKQAVNAIVEMLIPYLMRTFKELSYRHGWYKSHQDQRL---VPYNQFTEDYNLLP-- 772
            | |..::...|.:|..||.|:||             |.:....:::   |.......||.||.
 Frog   426 QSLATLLITSQILNQFVEALLPY-------------WLQKRSSRKIKKKVKSLNVDTDYTLLEQI 477

  Fly   773 --AENNSLYV----EYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGM 831
              .::...|:    :|||:.:.||:::|||..:|||.:.|:|||:.|:..||:||.|..:||...
 Frog   478 HLEKDMDTYLGTFDDYLELFLLFGYVSLFSCVYPLAAIFAVLNNLTEMYSDALKMCRVYKRPFSQ 542

  Fly   832 RARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMGDPELNNYLNFTLAVFNTKDFQ 896
            .:.:||||                 ::||.|..|..:|             .|.|
 Frog   543 PSANIGVW-----------------MLAFETMGIIAVV-------------TNCT---------- 567

  Fly   897 VQPLLGGSQHVNETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWA 961
               |||.|..|:      |.|::|..|           .|||     :...::.:..|:.||.:.
 Frog   568 ---LLGMSSQVS------TLFQDSKRD-----------LILT-----VAAIEHALLALKFILAFV 607

  Fly   962 VPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTELNGQQKSEGE 1009
            :||....:..::.|         :|:|...|:|     .|.|.|...|
 Frog   608 IPDKPYDIQVKLAR---------LEFESMEALK-----KNQQMKLSSE 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10353	NP_001245633.1	Anoct_dimer	183..392	CDD:292796	27/128 (21%)
		Anoctamin	395..977	CDD:282414	152/597 (25%)
ano10	XP_002937896.1	Anoctamin	195..621	CDD:367984	151/595 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920