DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10352 and AgaP_AGAP005972

DIOPT Version :9

Sequence 1:	NP_001259468.1	Gene:	CG10352 / 32147	FlyBaseID:	FBgn0030348	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_001688766.1	Gene:	AgaP_AGAP005972 / 1276646	VectorBaseID:	AGAP005972	Length:	320	Species:	Anopheles gambiae

Alignment Length:	307	Identity:	122/307 - (39%)
Similarity:	183/307 - (59%)	Gaps:	29/307 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VKYLKNMTEKERDEFFDSFDLVFCDCDGVVWYPLRDF---IPGSAEALAHLAHLGKDVTFVTNNS 65
            :|::..:::.||.:|..|||.:..|||||:|    :|   |||..:||..|...||.:.|::||.
Mosquito     9 MKHILELSKAERRQFLHSFDTLMSDCDGVLW----NFTGPIPGVDKALQLLRTDGKKLAFISNNG 69

  Fly    66 ISSVKEHIEKFEKQGHLKID--EHQIVHPAQTICDHLRSIKFEGLIYCLATSPFKEILVNAGFRL 128
            :.:::|:.:||...|   ||  |.:|||||.|...:|:||:....:||:.|..||:.|..|||::
Mosquito    70 MRTMEEYQKKFHSLG---IDALEEEIVHPALTTVHYLKSIRMRDAVYCIGTEVFKDYLRKAGFKV 131

  Fly   129 AQENGSGIITRLKDLHEA----IFS------GESVDAVIIDVDFNLSAAKLMRAHFQLQ-NPKCL 182
            .    .|...|..|..||    ::|      |..|.||:||:|.|||...||:|...|: :|.|:
Mosquito   132 L----DGPKERFPDSREANQVRVYSDYFEQHGPKVGAVVIDIDVNLSLQHLMKAKCYLERDPNCV 192

  Fly   183 FLAGAADALIPFGKG-EIIGPGAFIDVVTQAVGRQPITLGKPGEDLRKLLLERHREIPPSRVLFV 246
            |:|||.|.:||.... ::||||.|||::.:..||:.:.|||||:.|.:::||:.:...|.|||||
Mosquito   193 FIAGATDYIIPLDSSMDVIGPGYFIDILERTTGRKALILGKPGKALAQVVLEQFQITEPKRVLFV 257

  Fly   247 GDSLASDIGFARASGYQTLLVLTGGTKLEDVQRLPIDHSQMPDYLAD 293
            ||.:..|:||....|:|.||:|:|||. :|......|.:|:|:|.||
Mosquito   258 GDMMPQDMGFGTECGFQKLLMLSGGTP-KDALLAQTDPNQLPNYYAD 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10352	NP_001259468.1	PGP_euk	23..296	CDD:273635	116/288 (40%)
		Hydrolase_6	25..127	CDD:290083	42/106 (40%)
		Hydrolase_like	220..293	CDD:289983	32/72 (44%)
AgaP_AGAP005972	XP_001688766.1	PGP_euk	28..307	CDD:273635	116/288 (40%)
		Hydrolase_6	30..130	CDD:290083	42/106 (40%)
		Hydrolase_like	230..307	CDD:289983	34/75 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	65	1.000	Domainoid score	I17122
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26206
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19288
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.030