back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15739 and HDHD2

DIOPT Version :9

Sequence 1:	NP_001259467.1	Gene:	CG15739 / 32146	FlyBaseID:	FBgn0030347	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_115500.1	Gene:	HDHD2 / 84064	HGNCID:	25364	Length:	259	Species:	Homo sapiens

Alignment Length:	285	Identity:	62/285 - (21%)
Similarity:	105/285 - (36%)	Gaps:	67/285 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VVSDIDGVLWTFEQSIPRAADGYAALEQMGKHLTFLTNNSVRTSEQCVKLFAKIGMQVHPEQIWH 89
            |:.|:.|.|...:.::|.|.:....|......:.|:||.:..:.:..::...|:...:..::|:.
Human    10 VLVDLSGTLHIEDAAVPGAQEALKRLRGASVIIRFVTNTTKESKQDLLERLRKLEFDISEDEIFT 74

  Fly    90 PAKSIVSYLQSIKFEGLIYI--IASQSFKTVLREAGFQLLDGPNEFIEESYASLAEHIFGKEPVR 152
            ...:..|.|:..:...::.:  .|...||      |.|..| ||..:    ..||...|..:
Human    75 SLTAARSLLERKQVRPMLLVDDRALPDFK------GIQTSD-PNAVV----MGLAPEHFHYQ--- 125

  Fly   153 AVIIDVDFNLT---SPKIL--RAHLYLRHPECMLIEGATDRLLPVAKEVNIVGPGAFASILVEAS 212
              |::..|.|.   :|.|.  :|..|.|                  |:...:|||.|.:.|..|:
Human   126 --ILNQAFRLLLDGAPLIAIHKARYYKR------------------KDGLALGPGPFVTALEYAT 170

  Fly   213 GKQPITLGKPG--------RELGDLLVEHYQIVQPSRVLMIGDMLAQDVSFGRQCGFQTLLVLSG 269
            ..:...:|||.        |..|         .:|...:||||....||...:..|...:||.:|
Human   171 DTKATVVGKPEKTFFLEALRGTG---------CEPEEAVMIGDDCRDDVGGAQDVGMLGILVKTG 226

  Fly   270 --GCSKEE-------LLAETDPQRI 285
              ..|.||       |..|:.|..:
Human   227 KYRASDEEKINPPPYLTCESFPHAV 251

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.