Protein Alignment CG15739 and PDXP

DIOPT Version :9

• Sequence 1: NP_001259467.1
• Gene: CG15739 / 32146
• FlyBaseID: FBgn0030347
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_064711.1
• Gene: PDXP / 57026
• HGNCID: 30259
• Length: 296
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 92/288 - (31%)
• Similarity: 147/288 - (51%)
• Gaps: 27/288 - (9%)

  Fly    25 VVSDIDGVLWTFEQSIPRAADGYAALEQMGKHLTFLTNNSVRTSEQCVKLFAKIGM-QVHPEQIW 88
            |:.|.|||||..|:::|.|.:....|.:.||...|::|||.|...:....||::|. .:..||::
Human    22 VLFDCDGVLWNGERAVPGAPELLERLARAGKAALFVSNNSRRARPELALRFARLGFGGLRAEQLF 86

  Fly    89 HPAKSIVSYLQS-----IKFEGLIYIIASQSFKTVLREAGFQLLDGPNEFIEESYASLAEHIFGK 148
            ..|......|:.     ....|.::::..:..:..||.||.:|...|         |..:   |.
Human    87 SSALCAARLLRQRLPGPPDAPGAVFVLGGEGLRAELRAAGLRLAGDP---------SAGD---GA 139

  Fly   149 EP-VRAVIIDVDFNLTSPKILRAHLYLRHPECMLIEGATDR--LLPVAKEVNIVGPGAFASILVE 210
            .| ||||::..|.:.:..|:..|..:||.|||:|:  ||||  ..|::......|.|:.|:.:..
Human   140 APRVRAVLVGYDEHFSFAKLREACAHLRDPECLLV--ATDRDPWHPLSDGSRTPGTGSLAAAVET 202

  Fly   211 ASGKQPITLGKPGRELGDLLVEHYQIVQPSRVLMIGDMLAQDVSFGRQCGFQTLLVLSGGCSKEE 275
            |||:|.:.:|||...:.:.:.|::.| .|:|.||:||.|..|:.||.:||..|:|.|:|....||
Human   203 ASGRQALVVGKPSPYMFECITENFSI-DPARTLMVGDRLETDILFGHRCGMTTVLTLTGVSRLEE 266

  Fly   276 ---LLAETDPQRIPDYYADSVADVAQML 300
               .||......:|.||.:|:||:.:.|
Human   267 AQAYLAAGQHDLVPHYYVESIADLTEGL 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15739	NP_001259467.1	PGP_euk	23..296	CDD:273635	90/282 (32%)
		Hydrolase_6	25..125	CDD:290083	30/105 (29%)
		Hydrolase_like	219..295	CDD:289983	29/78 (37%)
PDXP	NP_064711.1	PGP_euk	18..290	CDD:273635	90/282 (32%)
		Substrate binding. /evidence=ECO:0000269|PubMed:18058037, ECO:0007744|PDB:2P27	58..60		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19288
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.880