DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BORCS5 and BORCS5

DIOPT Version :9

Sequence 1:	NP_572759.1	Gene:	BORCS5 / 32145	FlyBaseID:	FBgn0030346	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_477517.1	Gene:	BORCS5 / 118426	HGNCID:	17950	Length:	196	Species:	Homo sapiens

Alignment Length:	195	Identity:	71/195 - (36%)
Similarity:	114/195 - (58%)	Gaps:	9/195 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 QQSSASRAAARKSHPSGLTSAVKPKRPQSTASSHNIVIVRPGAIDAGEDV--DMDLARLRNIPQF 197
            :|||.:     :|.|:.|.|:|.|...:..|...:||:|..|: .|..:|  |.|:.:|:.||.|
Human     4 EQSSEA-----ESRPNDLNSSVTPSPAKHRAKMDDIVVVAQGS-QASRNVSNDPDVIKLQEIPTF 62

  Fly   198 LPVLRESITSATNTRDAEILERLNSQHLINICTRMQTHLNLCASYVASEQNHLVERTKVVSNSIT 262
            .|:|:..::..|:..:|: ||:|:||.::.:|.|.|.||:.||..||.:||.||:|.|.:..|:.
Human    63 QPLLKGLLSGQTSPTNAK-LEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVE 126

  Fly   263 TLFAGFVDMQKTYASYAEQFAKIRSISHQLSRCNSLLHENIASLEAINNFLDDEDRLEPFVWRTD 327
            |||:...:.||.||.||||..|:..:|..|.|....:.:.:..|:.:|:.|.:.:|||||..:.|
Human   127 TLFSFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLLDRLNSMLPEGERLEPFSMKPD 191

Fly 328 327
Human 192 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BORCS5	NP_572759.1	LOH1CR12	196..327	CDD:287167	49/130 (38%)
BORCS5	NP_477517.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32		9/27 (33%)
BORCS5	NP_477517.1	LOH1CR12	61..191	CDD:287167	49/129 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152706
Domainoid	1	1.000	95	1.000	Domainoid score	I7434
eggNOG	1	0.900	-	-		E1_KOG4515
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12188
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4790
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1446665at2759
OrthoFinder	1	1.000	-	-		FOG0007451
OrthoInspector	1	1.000	-	-		oto91360
orthoMCL	1	0.900	-	-		OOG6_107243
Panther	1	1.100	-	-	LDO	PTHR31634
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3444
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790