DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1847 and ROF1

DIOPT Version :9

Sequence 1:	NP_001368980.1	Gene:	CG1847 / 32144	FlyBaseID:	FBgn0030345	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001118695.1	Gene:	ROF1 / 822117	AraportID:	AT3G25230	Length:	562	Species:	Arabidopsis thaliana

Alignment Length:	332	Identity:	79/332 - (23%)
Similarity:	140/332 - (42%)	Gaps:	60/332 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SDMKPIRKEILNPGNAYIELTPGTRVKFH----------FQTRRAGDSRIIDDSRKMEKPMELVL 61
            :|...:.|::|..|:.|.....|..||..          |..:..|::         |:|.|...
plant   268 TDDNKVVKKVLKEGDGYERPNEGAVVKVKLIGKLQDGTVFLKKGHGEN---------EEPFEFKT 323

  Fly    62 GKKFKLEVWELIVQQMSLNEVAKFTVHKSLCAQYPFISKTLRDIGKKPEERRHCCGMTLQNEGIG 126
            .::..::..:..|.:|...|||..|:.    .:|.|.|                      ||
plant   324 DEEQVVDGLDRAVMKMKKGEVALVTID----PEYAFGS----------------------NE--- 359

  Fly   127 YTDLDELLQNP--SDLEFIIELFSIELPEQYEKERWQMSDDEKMLATSTLRERGNNFYKASRFTE 189
              ...||...|  |.:.:.::|.:.:    .|:|.|.|:.:||:.|.|..:|.||:.:|..:::.
plant   360 --SQQELAVVPPNSTVTYEVDLLTFD----KERESWDMNTEEKIEAASKKKEEGNSKFKGGKYSL 418

  Fly   190 AETCYREAVGIVEQLMLKEKPHDEEWQELAAIKTPLLLNYAQCRLIAGDFYAVIEHCNEVLTLDP 254
            |...|.:||..:|   ......:||.::..|:|....||.|.|:|...|:....:.|.:||.|:.
plant   419 ASKRYEKAVKFIE---YDTSFSEEEKKQAKALKVACNLNDAACKLKLKDYKQAEKLCTKVLELES 480

  Fly   255 RNVKALFRRAKAHAGAWNPAQARRDFLDALALDASLKSTVSKELKSIEDQQQARNVQDRIHMQKL 319
            .|||||:|||:|:....:...|..|...||.:|.:.:. |..|.|.::::.:..|.::......:
plant   481 TNVKALYRRAQAYMELSDLDLAEFDVKKALEIDPNNRE-VKLEQKRLKEKMKEFNKKEAKFYGNM 544

  Fly   320 FXNISCV 326
            |..:..:
plant   545 FAKLRII 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1847	NP_001368980.1	FKBP_C	23..>92	CDD:395196	15/78 (19%)
		3a0801s09	150..>308	CDD:273380	48/157 (31%)
		TPR repeat	173..217	CDD:276809	11/43 (26%)
		TPR repeat	222..252	CDD:276809	10/29 (34%)
		TPR repeat	257..285	CDD:276809	11/27 (41%)
ROF1	NP_001118695.1	FKBP_C	50..142	CDD:278674
		FKBP_C	283..380	CDD:278674	24/136 (18%)
		TPR_11	400..479	CDD:290150	23/81 (28%)
		TPR repeat	400..438	CDD:276809	10/40 (25%)
		TPR_11	443..514	CDD:290150	25/70 (36%)
		TPR repeat	443..478	CDD:276809	11/34 (32%)
		TPR_1	483..516	CDD:278916	13/32 (41%)
		TPR repeat	483..511	CDD:276809	11/27 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910