DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1847 and TWD1

DIOPT Version :9

Sequence 1:	NP_001368980.1	Gene:	CG1847 / 32144	FlyBaseID:	FBgn0030345	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_188801.2	Gene:	TWD1 / 821718	AraportID:	AT3G21640	Length:	365	Species:	Arabidopsis thaliana

Alignment Length:	346	Identity:	83/346 - (23%)
Similarity:	147/346 - (42%)	Gaps:	63/346 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IRKEILNPGNAYIELTPGTRVK------FHFQTRRAGDSRIIDDSRKMEKPMELVLGKKFKLEVW 70
            :.|:|:..|:       |::..      .|::..........:|:...::|:||||||: |.|:.
plant    51 VSKQIIKEGH-------GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKE-KKELA 107

  Fly    71 ELIVQQMSLNEVAKFTVHKSLCAQYPFISKTLRDIGKKPEERRHCCGMTLQNEG-IGYTDLDELL 134
            .|.:...|:....:..||......|          ||               || ..:.::..:
plant   108 GLAIGVASMKSGERALVHVGWELAY----------GK---------------EGNFSFPNVPPM- 146

  Fly   135 QNPSDLEFIIELFSIELPEQYEKERWQMSDDEKMLATSTLRERGNNFYKASRFTEAETCYREAVG 199
               :||.:.:|:...:..:: .|.|..|:.:|::.|....:..||:.:|..:..||...|..|:.
plant   147 ---ADLLYEVEVIGFDETKE-GKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIA 207

  Fly   200 -----IVEQLMLKEKPHDEEWQELA-AIKTPLLLNYAQCRLIAGDFYAVIEHCNEVLTLDPRNVK 258
                 .:.||..|       :|::| |:|.|..||.|.|.:....:...|.|||.|||.:.:|.|
plant   208 YMGDDFMFQLYGK-------YQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPK 265

  Fly   259 ALFRRAKAHAGAWNPAQARRDFLDALALDASLKSTVSKELKSIEDQQQARNVQDRIHMQKLFXNI 323
            |||||.||.|.......||.||..|.......|: :.:||:::.:|::|...:.:...:.:|...
plant   266 ALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKA-IRRELRALAEQEKALYQKQKEMYKGIFKGK 329

  Fly   324 ----SCVNVLLMLLVYWSSYL 340
                :....|..|:|.|..::
plant   330 DEGGAKSKSLFWLIVLWQWFV 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1847	NP_001368980.1	FKBP_C	23..>92	CDD:395196	16/74 (22%)
		3a0801s09	150..>308	CDD:273380	50/163 (31%)
		TPR repeat	173..217	CDD:276809	10/48 (21%)
		TPR repeat	222..252	CDD:276809	12/29 (41%)
		TPR repeat	257..285	CDD:276809	14/27 (52%)
TWD1	NP_188801.2	FKBP_C	62..156	CDD:395196	23/123 (19%)
		PRK15331	196..310	CDD:357168	41/121 (34%)
		TPR repeat	230..259	CDD:276809	11/28 (39%)
		TPR repeat	264..292	CDD:276809	14/27 (52%)
		TPR repeat	298..323	CDD:276809	5/25 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910