DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1847 and zda

DIOPT Version :9

Sequence 1:	NP_001368980.1	Gene:	CG1847 / 32144	FlyBaseID:	FBgn0030345	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	74/348 - (21%)
Similarity:	128/348 - (36%)	Gaps:	93/348 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KPIRKEILNPGNAYIELTPGTRV--KFHFQTRRAGDSRIIDDSRKMEKPMELVLGKKFKLEVWEL 72
            :|||.|::.. |...:|..||.|  :.:||. ..||..:|                    :..::
  Fly    81 RPIRGELVTV-NFTGKLDNGTVVENELNFQC-HVGDYEVI--------------------QGLDM 123

  Fly    73 IVQQMSLNEVAKFTVHKSLCAQYPFISKTLRDIGKKPEERRHCCGMTLQNEGIGYTDLDELLQNP 137
            ::..:.:.||::.:|                      :.|.....:.|:.||    :.:.|:...
  Fly   124 VLPMLQVGEVSQVSV----------------------DSRFGYGSLGLKKEG----ESEYLVPPD 162

  Fly   138 SDLEFIIELFSIELPEQYEKERWQMSDDEKMLATSTLRERGNNFYKASRFTEAETCYREAVGIVE 202
            :.|.:.|||..|:..|..:.:.:::.   :...|.. :||.|.|||.|.||.|...||.|:..::
  Fly   163 AHLTYEIELLDIKYEEFADLKSFEIL---RKYGTRK-KERANFFYKRSEFTTAIHLYRRALDFLD 223

  Fly   203 QLMLKEKPHDEEWQ----ELAAIKTPLLL--------NYAQCRLIAGDFYAVIEHCNEVLTLDPR 255
            .   ::...|.|:.    ||:...|..||        |.|..::....:.|.::....||...|.
  Fly   224 N---RDGDPDSEFDKEDLELSNSDTQTLLEDRLIVYNNLAMTQIKIAAYDAALQSVEHVLRCQPN 285

  Fly   256 NVKALFRRAKAHAGAWNPAQA---------------------RRDFLDALALDASLKSTVSKEL- 298
            |.|||:|:.:...|..:...|                     .|.|:.|...:.:.|....|.|
  Fly   286 NSKALYRKGRILEGKADTQGAIKLLQKVATLEPENRAVQSDLARLFIKARREEHNEKEMYQKMLG 350

  Fly   299 --KSIEDQQQARNVQDRIHMQKL 319
              |.:|.....|..|..:...||
  Fly   351 QAKKMEQNTATRQKQPLVDNSKL 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1847	NP_001368980.1	FKBP_C	23..>92	CDD:395196	12/70 (17%)
		3a0801s09	150..>308	CDD:273380	43/193 (22%)
		TPR repeat	173..217	CDD:276809	15/47 (32%)
		TPR repeat	222..252	CDD:276809	8/37 (22%)
		TPR repeat	257..285	CDD:276809	9/48 (19%)
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	25/138 (18%)
		TPR_11	196..284	CDD:290150	25/90 (28%)
		TPR repeat	196..220	CDD:276809	13/23 (57%)
		TPR repeat	252..282	CDD:276809	5/29 (17%)
		TPR_11	255..318	CDD:290150	13/62 (21%)
		TPR repeat	287..313	CDD:276809	6/25 (24%)
		TPR repeat	321..349	CDD:276809	5/27 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910