DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1847 and Tom70

DIOPT Version :9

Sequence 1:	NP_001368980.1	Gene:	CG1847 / 32144	FlyBaseID:	FBgn0030345	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_609536.1	Gene:	Tom70 / 34618	FlyBaseID:	FBgn0032397	Length:	589	Species:	Drosophila melanogaster

Alignment Length:	192	Identity:	51/192 - (26%)
Similarity:	78/192 - (40%)	Gaps:	50/192 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 IELFSIEL----PEQYEKERWQMSDD--EKMLATSTLRE------RGNNFYKASRFTEAETCYRE 196
            ||..:|.|    |:| |.||.|.|.:  ||:   |.|:|      .|||.|:..::.||...|.:
  Fly    55 IEKQAISLDGTAPDQ-ELERNQKSAELGEKL---SPLKEANNYKTEGNNCYRNGKYDEAIKFYDK 115

  Fly   197 AVGIVEQLMLKEKPHDEEWQELAAIKTPLLLNYAQCRLIAGDFYAVIEHCNEVLTLDPRNVKALF 261
            |:         :|...|...::|........:|...:    .:..|.|.|...|..:||..||.:
  Fly   116 AI---------DKCPKEHRTDMAIFYQNRAASYEMLK----KWSNVKEDCTASLEFNPRYAKAYY 167

  Fly   262 RRAKAHAGAWNPAQARRDF---LDALALDASLK-----------STVSKELKSIEDQQQARN 309
            |||:||       :|.:|.   ||.:.....|:           ..|.||...::.::..||
  Fly   168 RRARAH-------EATKDMNECLDDVTATCILEMFQNNQTIMFADRVLKETGRLDAEKGMRN 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1847	NP_001368980.1	FKBP_C	23..>92	CDD:395196
		3a0801s09	150..>308	CDD:273380	46/183 (25%)
		TPR repeat	173..217	CDD:276809	12/49 (24%)
		TPR repeat	222..252	CDD:276809	5/29 (17%)
		TPR repeat	257..285	CDD:276809	11/30 (37%)
Tom70	NP_609536.1	TPR_11	89..160	CDD:290150	17/83 (20%)
		TPR repeat	90..118	CDD:276809	8/36 (22%)
		TPR repeat	123..158	CDD:276809	7/38 (18%)
		TPR repeat	296..324	CDD:276809
		TPR_11	333..399	CDD:290150
		TPR repeat	334..362	CDD:276809
		TPR repeat	367..397	CDD:276809
		TPR repeat	402..437	CDD:276809
		TPR_16	413..477	CDD:290168
		TPR repeat	443..471	CDD:276809
		TPR repeat	476..507	CDD:276809
		TPR_11	486..539	CDD:290150
		TPR repeat	512..539	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1535
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.030