DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1847 and Fkbp6

DIOPT Version :9

Sequence 1:	NP_001368980.1	Gene:	CG1847 / 32144	FlyBaseID:	FBgn0030345	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001099392.1	Gene:	Fkbp6 / 288597	RGDID:	1308926	Length:	327	Species:	Rattus norvegicus

Alignment Length:	345	Identity:	77/345 - (22%)
Similarity:	131/345 - (37%)	Gaps:	77/345 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SRSKSDMKPIRKEILNP----GNAYIELTPGTRVKFHFQTRRAGDSRIIDDS---------RKME 54
            ||.::.:.|.|.:..:|    ....::::....|........|||....|.|         ..|:
  Rat     5 SRLRNGIPPSRDDCQSPYERLSQRMLDISGDRGVLKDIIREGAGDPVTPDASVLVKYSGYLEHMD 69

  Fly    55 KPME----------LVLGKKFKLEVWELIVQQMSLNEVAKFTVHKSLCAQYPFISKTLRDIGKKP 109
            ||.:          :.||:...|...||.:..|...|:|:|..                    ||
  Rat    70 KPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLF--------------------KP 114

  Fly   110 EERRHCCGMTLQNEGIGYTDLDELLQNPSDLEFIIELFSIELPEQYEKERW---------QMSDD 165
                        ....|......|:...:.:.|.|||  |:..:..|.:::         |....
  Rat   115 ------------TYAYGTLGCPPLIPPNATVLFEIEL--IDFLDSAESDKFCALSAEQQEQFPLQ 165

  Fly   166 EKMLATSTLRERGNNFYKASRFTEAETCYREAVGIV-EQLMLKEKPHDEEWQELAAIKTPLLLNY 229
            :.:...:|.||.||..::.:||.:|:..|:.|:.:: .:|.:.|:.|..|..||..:   |.|::
  Rat   166 KVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVL---LNLSF 227

  Fly   230 AQCRLIAGDFYAV-IEHCNEVLTLDPRNVKALFRRAKAHAGAWNPAQARRDFLDALALDASLKST 293
            ...:|   |..|: :.:..:.|.:|.||.|||||..:|........|| ||||.....:......
  Rat   228 VYLKL---DRPAMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQA-RDFLVRAQKEQPCNHD 288

  Fly   294 VSKELKSIEDQQQARNVQDR 313
            ::.|||.:....  |:..||
  Rat   289 INNELKKLSSHY--RDYVDR 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1847	NP_001368980.1	FKBP_C	23..>92	CDD:395196	18/87 (21%)
		3a0801s09	150..>308	CDD:273380	42/168 (25%)
		TPR repeat	173..217	CDD:276809	14/44 (32%)
		TPR repeat	222..252	CDD:276809	6/30 (20%)
		TPR repeat	257..285	CDD:276809	12/27 (44%)
Fkbp6	NP_001099392.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		4/14 (29%)
		FKBP_C	51..140	CDD:395196	22/122 (18%)
		TPR	<164..284	CDD:223533	37/126 (29%)
		TPR 1	171..204		10/32 (31%)
		TPR repeat	218..248	CDD:276809	8/35 (23%)
		TPR 2	219..252		8/38 (21%)
		TPR 3	253..286		12/33 (36%)
		TPR repeat	253..281	CDD:276809	12/28 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910