DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1847 and Spag1

DIOPT Version :9

Sequence 1:NP_001368980.1 Gene:CG1847 / 32144 FlyBaseID:FBgn0030345 Length:390 Species:Drosophila melanogaster
Sequence 2:NP_001346910.1 Gene:Spag1 / 26942 MGIID:1349387 Length:913 Species:Mus musculus


Alignment Length:325 Identity:70/325 - (21%)
Similarity:113/325 - (34%) Gaps:82/325 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 RSKSDMKPIRKEI-LNPGNAYIELTPGTRVKFHFQTRRAGDSRIIDDSRK-MEKPMELVLGKKFK 66
            |..|.::...|.: |:|||....|...|..|...:.:.|     :||.|| ::...:..|.||..
Mouse   273 RWSSALEDCEKALELDPGNVKALLRRATTYKHQNKLQEA-----VDDLRKVLQVEPDNDLAKKTL 332

  Fly    67 LEV-----------------WELIVQQM------------------SLNEVAKFTVHKSLCAQYP 96
            .||                 ..::::::                  ..:|.|...:.|.|..:  
Mouse   333 SEVERDLKNSEPVSELQTKGKRMVIEEVENSGDEGGKGSADEREDGGSDEAAMGNIQKKLMVR-- 395

  Fly    97 FISKTLRDIGKKPEERRHCCGMTLQNEGIGYTDLDELLQNPSDLEFIIELFSIELPEQYEKERWQ 161
                  |..|.:...|....|...:.:|                 .:.|..:....:.:..|..:
Mouse   396 ------RSEGGRRSRRGRTPGPRAEQQG-----------------GLRETATASTGDSHYPEEPR 437

  Fly   162 MSDDEKMLATSTLRERGNNFYKASRFTEAETCYREAVGIVEQLMLKEKPHDEEWQELAAIKTPLL 226
            .:|:     .|.|:.|||..::..:|.||...|..|:.   ||   |........||:.    |.
Mouse   438 AADN-----PSGLKRRGNELFRGGQFAEAAAQYSVAIA---QL---EPTGSANADELSI----LY 487

  Fly   227 LNYAQCRLIAGDFYAVIEHCNEVLTLDPRNVKALFRRAKAHAGAWNPAQARRDFLDALALDASLK 291
            .|.|.|.|..|:....|:.||..|.|.|.:||.|.|||.|:........|..|:...|.:|..::
Mouse   488 SNRAACYLKEGNCRDCIQDCNRALELHPFSVKPLLRRAMAYETLEQYRNAYVDYKTVLQIDCGIQ 552

  Fly   292  291
            Mouse   553  552

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1847NP_001368980.1 FKBP_C 23..>92 CDD:395196 16/104 (15%)
3a0801s09 150..>308 CDD:273380 40/142 (28%)
TPR repeat 173..217 CDD:276809 12/43 (28%)
TPR repeat 222..252 CDD:276809 10/29 (34%)
TPR repeat 257..285 CDD:276809 9/27 (33%)
Spag1NP_001346910.1 3a0801s09 214..698 CDD:273380 70/325 (22%)
TPR repeat 229..253 CDD:276809
TPR repeat 258..287 CDD:276809 3/13 (23%)
TPR repeat 292..320 CDD:276809 8/32 (25%)
TPR repeat 445..471 CDD:276809 9/28 (32%)
TPR repeat 483..513 CDD:276809 11/33 (33%)
TPR repeat 518..546 CDD:276809 9/27 (33%)
TPR repeat 619..646 CDD:276809
PLN03088 631..>807 CDD:215568
TPR repeat 651..681 CDD:276809
RPAP3_C 789..878 CDD:404718
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1535
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

Return to query results.
Submit another query.