DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1847 and fkb-6

DIOPT Version :9

Sequence 1:	NP_001368980.1	Gene:	CG1847 / 32144	FlyBaseID:	FBgn0030345	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_508026.1	Gene:	fkb-6 / 180371	WormBaseID:	WBGene00001431	Length:	431	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	92/417 - (22%)
Similarity:	152/417 - (36%)	Gaps:	110/417 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SRSKSDMKP-----IRKEILNPGNAYIELTPGTRVKFHFQTRRAGDSRIIDDSRKMEKPMELVLG 62
            |..|.|:.|     :.|.|...|...::.|.||.||.|:.......:: .|.||.........||
Worm     2 SGEKIDITPKKDGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTLENGTK-FDSSRDRGDQFSFNLG 65

  Fly    63 KKFKLEVWELIVQQMSLNEVAKFTVHK-----------------SLCAQYPFISKTLRDI----- 105
            :...::.|:|.|..|:..|||:||:..                 :|..:......:..||
Worm    66 RGNVIKGWDLGVATMTKGEVAEFTIRSDYGYGDAGSPPKIPGGATLIFEVELFEWSAEDISPDRD 130

  Fly   106 ----------GKK---PEER----RHCCGMTLQ---------NEGIGYTDLDELLQNPSDLEFII 144
                      |.|   |.:.    .||.| |.|         |..||....:.|   |..:|..:
Worm   131 GTILRTIIVEGSKNSFPNDTSKVLAHCVG-TYQGTEFYNREVNFHIGEGSEEGL---PEGVERAL 191

  Fly   145 ELFSI-----------------------ELP-----------EQYEK--ERWQMSDDEKMLATST 173
            ..|.:                       .:|           :::||  ..|:|:.:||:.|...
Worm   192 RRFQLGEKSKIEIRGHKYTYGNSPPAGSNIPVNATLEFTIFLKEFEKVPATWEMTAEEKLDAAKQ 256

  Fly   174 LRERGNNFYKASRFTEAETCYREAVGIVEQLMLKEKPHDEEWQELAAIKTPLLLNYAQCRLIA-- 236
            .::||..:.:......|...|:.|    |:::..||..|.|  ::|..:|.|...|....|:.
Worm   257 AKDRGTMYLQKGNLKLAYNKYKRA----EEVLEYEKSTDPE--KMAERETILNGAYLNLSLVCSK 315

  Fly   237 -GDFYAVIEHCNEVLTLDPRNVKALFRRAKAHAGAWNPAQARRDFLDALALDASLKSTVSKEL-- 298
             .:....|:.|::||...|.|||||:|:|.|.........|.:.|...:.::...|:...:.:
Worm   316 QNEQLECIKWCDKVLETKPGNVKALYRKATALLTMNEVRDAMKLFEKIVEVEPENKAAAQQIIVC 380

  Fly   299 -KSIEDQQQARNVQDRIHMQKLFXNIS 324
             .:|.:|    |.:|:...:.||..||
Worm   381 RNTIREQ----NERDKKRFKNLFAKIS 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1847	NP_001368980.1	FKBP_C	23..>92	CDD:395196	20/85 (24%)
		3a0801s09	150..>308	CDD:273380	41/176 (23%)
		TPR repeat	173..217	CDD:276809	10/43 (23%)
		TPR repeat	222..252	CDD:276809	8/32 (25%)
		TPR repeat	257..285	CDD:276809	9/27 (33%)
fkb-6	NP_508026.1	FKBP_C	26..117	CDD:278674	21/91 (23%)
		TPR_11	254..334	CDD:290150	19/85 (22%)
		TPR repeat	254..282	CDD:276809	5/31 (16%)
		TPR repeat	291..332	CDD:276809	11/42 (26%)
		TPR_11	305..368	CDD:290150	17/62 (27%)
		TPR_1	337..370	CDD:278916	9/32 (28%)
		TPR repeat	337..365	CDD:276809	9/27 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910