DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1847 and aipr-1

DIOPT Version :9

Sequence 1:	NP_001368980.1	Gene:	CG1847 / 32144	FlyBaseID:	FBgn0030345	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_495339.1	Gene:	aipr-1 / 174092	WormBaseID:	WBGene00016966	Length:	342	Species:	Caenorhabditis elegans

Alignment Length:	333	Identity:	113/333 - (33%)
Similarity:	176/333 - (52%)	Gaps:	27/333 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 KEILNPGNAYI-ELTPGTRVKFHFQT------RRAGDS--------RIIDDSRK-----MEKPME 58
            |..::.|...| |...||:..||:|.      ...|..        :.|||:||     ..||:|
Worm     9 KRTISGGKGKISEYCDGTKAVFHYQALFPIEKHEKGQPLSLEKDAFKSIDDTRKPWPHGYGKPLE 73

  Fly    59 LVLGKKFKLEVWELIVQQMSLNEVAKFTVHKSLCAQYPFISKTLRDIGKKPEERR------HCCG 117
            :|.||||:|.|:|..::.|.::|:::|.|......||||:||.|||:.|..:.:.      |.|.
Worm    74 IVFGKKFQLPVFEQCLKTMLVDEISQFDVECIDLVQYPFVSKKLRDLVKPCDGKHSHAHTTHMCA 138

  Fly   118 MTLQNEGIGYTDLDELLQNPSDLEFIIELFSIELPEQYEKERWQMSDDEKMLATSTLRERGNNFY 182
            .::. :|.||.:||||::||..|.|:..|..:..|:||..:.||:.:|:|:.:...||::||..:
Worm   139 ASIA-QGTGYEELDELMKNPRPLRFVFHLLQVFEPDQYVHDSWQLDEDDKLKSVEALRQKGNELF 202

  Fly   183 KASRFTEAETCYREAVGIVEQLMLKEKPHDEEWQELAAIKTPLLLNYAQCRLIAGDFYAVIEHCN 247
            ....:.||...||:|:..::.|:|:|||.:.||.||.....||..|.:||.|..||.:...|..:
Worm   203 VQKDYKEAIDAYRDALTRLDTLILREKPGEPEWVELDRKNIPLYANMSQCYLNIGDLHEAEETSS 267

  Fly   248 EVLTLDPRNVKALFRRAKAHAGAWNPAQARRDFLDALALDASLKSTVSKELKSIEDQQQARNVQD 312
            |||..:..|.|||||||||...||...:|..|....|....:..|.|::|:|.:.:::..:....
Worm   268 EVLKREETNEKALFRRAKARIAAWKLDEAEEDLKLLLRNHPAAASVVAREMKIVTERRAEKKADS 332

  Fly   313 RIHMQKLF 320
            |:...|:|
Worm   333 RVTYSKMF 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1847	NP_001368980.1	FKBP_C	23..>92	CDD:395196	28/88 (32%)
		3a0801s09	150..>308	CDD:273380	56/157 (36%)
		TPR repeat	173..217	CDD:276809	16/43 (37%)
		TPR repeat	222..252	CDD:276809	12/29 (41%)
		TPR repeat	257..285	CDD:276809	13/27 (48%)
aipr-1	NP_495339.1	TPR repeat	191..237	CDD:276809	16/45 (36%)
		TPR_1	191..>218	CDD:278916	8/26 (31%)
		TPR_11	192..271	CDD:290150	29/78 (37%)
		TPR repeat	242..272	CDD:276809	12/29 (41%)
		TPR_11	245..308	CDD:290150	26/62 (42%)
		TPR repeat	277..305	CDD:276809	13/27 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159136
Domainoid	1	1.000	80	1.000	Domainoid score	I5566
eggNOG	1	0.900	-	-		E1_KOG0545
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2959
Inparanoid	1	1.050	193	1.000	Inparanoid score	I2543
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48583
OrthoDB	1	1.010	-	-		D1278789at2759
OrthoFinder	1	1.000	-	-		FOG0002564
OrthoInspector	1	1.000	-	-		oto20794
orthoMCL	1	0.900	-	-		OOG6_106917
Panther	1	1.100	-	-	LDO	PTHR11242
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1535
SonicParanoid	1	1.000	-	-		X1687
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800