DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1847 and Fkbp5

DIOPT Version :9

Sequence 1:NP_001368980.1 Gene:CG1847 / 32144 FlyBaseID:FBgn0030345 Length:390 Species:Drosophila melanogaster
Sequence 2:NP_034350.1 Gene:Fkbp5 / 14229 MGIID:104670 Length:456 Species:Mus musculus


Alignment Length:379 Identity:82/379 - (21%)
Similarity:145/379 - (38%) Gaps:100/379 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 GTRVKFHFQTRRAGDSRIIDDSRKMEKPMELVLGKKFKLEVWELIVQQMSLNEVA---------- 83
            |.:|..|:: ....|.:..|.|...:||....||:...::.|::.|..|...|:.          
Mouse    50 GDKVYVHYK-GMLSDGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAY 113

  Fly    84 -------KFTVHKSLCAQYPFI----------SKTLRDIGKK------PEE----RRH---CCG- 117
                   |...:.:|..:...:          |..:|.|.:|      |.|    :.|   ||| 
Mouse   114 GSAGHLQKIPSNATLFFEIELLDFKGEDLFEDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGG 178

  Fly   118 ----------------------------MTLQNE-----------GIGYTDLDELLQNP-SDLEF 142
                                        :.:|.|           |.|.....:...:| ::|.:
Mouse   179 RTFDCRDVVFVVGEGEDHDIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMY 243

  Fly   143 IIELFSIELPEQYEKERWQMSDDEKMLATSTLRERGNNFYKASRFTEAETCYREAVGIVEQ---L 204
            .:.|.|.|    ..||.|:|...||:...:.::|:|..::|..::|:|...||:.|..:|.   |
Mouse   244 EVTLKSFE----KAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGL 304

  Fly   205 MLKEKPHDEEWQELAAIKTPLLLNYAQCRLIAGDFYAVIEHCNEVLTLDPRNVKALFRRAKAHAG 269
            ..||....|.:. |||     .||.|.|.|...::...:|.|::.|.||..|.|.|:||.:|...
Mouse   305 SEKESKASESFL-LAA-----FLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLL 363

  Fly   270 AWNPAQARRDFLDALALDASLKSTVSKELKSIEDQQQARNVQDRIHMQKLFXNI 323
            ..:...|:.||...||::...:: ...::...:.:.:..|.:||    ::: |:
Mouse   364 MNDFESAKGDFEKVLAVNPQNRA-ARLQISMCQRKAKEHNERDR----RVYANM 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1847NP_001368980.1 FKBP_C 23..>92 CDD:395196 15/79 (19%)
3a0801s09 150..>308 CDD:273380 44/160 (28%)
TPR repeat 173..217 CDD:276809 13/46 (28%)
TPR repeat 222..252 CDD:276809 8/29 (28%)
TPR repeat 257..285 CDD:276809 8/27 (30%)
Fkbp5NP_034350.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
FKBP_C 44..135 CDD:278674 16/85 (19%)
TPR_11 267..347 CDD:290150 24/85 (28%)
TPR 1 268..301 9/32 (28%)
TPR repeat 268..296 CDD:276809 7/27 (26%)
TPR 2 317..350 13/37 (35%)
TPR_11 319..382 CDD:290150 22/67 (33%)
TPR 319..350 CDD:197478 11/35 (31%)
TPR repeat 319..345 CDD:276809 8/30 (27%)
TPR repeat 350..380 CDD:276809 10/29 (34%)
TPR 3 351..384 10/32 (31%)
TPR_1 352..384 CDD:278916 10/31 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 421..456
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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