DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1847 and Aipl1

DIOPT Version :10

Sequence 1:NP_001368980.1 Gene:CG1847 / 32144 FlyBaseID:FBgn0030345 Length:390 Species:Drosophila melanogaster
Sequence 2:XP_006532060.1 Gene:Aipl1 / 114230 MGIID:2148800 Length:333 Species:Mus musculus


Alignment Length:316 Identity:119/316 - (37%)
Similarity:188/316 - (59%) Gaps:13/316 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 DMKPIRKEILNPGNAYI-ELTPGTRVKFHFQTRRAGDSR-IIDDSRKMEKPMELVLGKKFKLEVW 70
            :::.::|.||:.|...: ....|:||.|||:|.:..|.| :||||:::.:||.:::|..||||||
Mouse    13 NVEGVKKTILHGGTGELPSFITGSRVTFHFRTMKCDDERTVIDDSKQVGQPMSIIIGNMFKLEVW 77

  Fly    71 ELIVQQMSLNEVAKF---TVHKSLCAQYPFISKTLRDI--GKKPEE-RRHCCGMT--LQNEGIGY 127
            |.::..|.|.|||:|   |:|..:   ||.:|::||.:  ||.|.. ..|.||:.  .....:||
Mouse    78 ETLLTSMRLGEVAEFWCDTIHTGV---YPMLSRSLRQVAEGKDPTSWHVHTCGLANMFAYHTLGY 139

  Fly   128 TDLDELLQNPSDLEFIIELFSIELPEQYEKERWQMSDDEKMLATSTLRERGNNFYKASRFTEAET 192
            .|||||.:.|..|.|:|||..:|.|.:|::|.|.::::|:|.|...|...||..||..|:.:|.|
Mouse   140 EDLDELQKEPQPLVFLIELLQVEAPNEYQRETWNLNNEERMQAVPLLHGEGNRLYKLGRYDQAAT 204

  Fly   193 CYREAVGIVEQLMLKEKPHDEEWQELAAIKTPLLLNYAQCRLIAGDFYAVIEHCNEVLTLDPRNV 257
            .|:||:..:..|..||||.:.||.:|..:...|:|||.||.|...::|.|:||.:::|...|..|
Mouse   205 KYQEAIVCLRNLQTKEKPWEVEWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIV 269

  Fly   258 KALFRRAKAHAGAWNPAQARRDFLDALALDASLKSTVSKELKSIEDQQQARNVQDR 313
            ||.:.||:|||..||..:|:.|....|.|:.|::..|.:||:.:|.:...:..::|
Mouse   270 KAYYMRARAHAEVWNAEEAKADLEKVLELEPSMRKAVLRELRLLESRLADKQEEER 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1847NP_001368980.1 FKBP_C 23..>92 CDD:459735 31/73 (42%)
TPR repeat 173..217 CDD:276809 18/43 (42%)
NrfG 174..287 CDD:443378 45/112 (40%)
TPR repeat 222..252 CDD:276809 12/29 (41%)
TPR repeat 257..285 CDD:276809 12/27 (44%)
Aipl1XP_006532060.1 FKBP_C 35..>94 CDD:473184 29/58 (50%)
TPR repeat 185..229 CDD:276809 18/43 (42%)
Spy 190..>305 CDD:443119 46/114 (40%)
TPR repeat 234..264 CDD:276809 12/29 (41%)
TPR repeat 269..297 CDD:276809 12/27 (44%)

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