DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1847 and fkbp4

DIOPT Version :9

Sequence 1:	NP_001368980.1	Gene:	CG1847 / 32144	FlyBaseID:	FBgn0030345	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_012810222.1	Gene:	fkbp4 / 100379681	XenbaseID:	XB-GENE-948088	Length:	450	Species:	Xenopus tropicalis

Alignment Length:	317	Identity:	83/317 - (26%)
Similarity:	133/317 - (41%)	Gaps:	57/317 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IRKEILNPGNAYIELTPGTRVKFHFQTRRAGDSRIIDDSRKMEKPMELVLGKKFKLEV---WELI 73
            |.:.|...|..|.:...|..|:.|.:....|  |:.|     |:.::..:|:...:.:   .|..
Frog   146 IIRRIQVKGEGYSKPNEGAVVEIHVKGTHEG--RVFD-----ERELKFEVGEGESIGIPPGVETA 203

  Fly    74 VQQMSLNEVAKFTVHKSLCAQYPFISKTLRDIGKKPEERRHCCGMTLQNEGIGYTDLDELLQNP- 137
            :|||...|.|...:                    ||:            .|.|.|. .|..|.|
Frog   204 IQQMEKGEKAILYL--------------------KPK------------YGFGTTG-SEKYQIPP 235

  Fly   138 -SDLEFIIELFSIELPEQYEKERWQMSDDEKMLATSTLRERGNNFYKASRFTEAETCYREAVGIV 201
             ::|::.|.|.|.|    ..||.|:|:.:||:.....::|||..::|..|:.:|...|::.:..:
Frog   236 GAELQYDIRLKSFE----KAKESWEMNAEEKLEQGCLVKERGTQYFKDGRYRQATIQYKKIIQWL 296

  Fly   202 EQLMLKEKPHDEEWQELAAIKTPLLLNYAQCRLIAGDFYAVIEHCNEVLTLDPRNVKALFRRAKA 266
            |......|..|.:.:.|....:   ||.|.|.|..|:..|.::|||:.|.|||.|.|.||||.:|
Frog   297 EHESGLSKEEDAKAKSLILAAS---LNLAACYLKLGEHRAALDHCNKALELDPSNEKGLFRRGEA 358

  Fly   267 HAGAWNPAQARRDFLDALALDASLKSTVSKELKSIEDQQQARNVQDRIHMQKLFXNI 323
            :....:..|||.||...|.|     ...:|..::...|.|.|..|.....:|:: |:
Frog   359 YMCTNDLEQARNDFTKVLQL-----YPANKAARAQLGQCQVRIRQQTEREKKIYANM 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1847	NP_001368980.1	FKBP_C	23..>92	CDD:395196	15/71 (21%)
		3a0801s09	150..>308	CDD:273380	49/157 (31%)
		TPR repeat	173..217	CDD:276809	10/43 (23%)
		TPR repeat	222..252	CDD:276809	11/29 (38%)
		TPR repeat	257..285	CDD:276809	11/27 (41%)
fkbp4	XP_012810222.1	FKBP_C	39..130	CDD:365980
		FKBP_C	156..246	CDD:365980	25/129 (19%)
		TPR	<237..380	CDD:223533	50/154 (32%)
		TPR repeat	270..294	CDD:276809	7/23 (30%)
		TPR repeat	307..344	CDD:276809	13/39 (33%)
		TPR repeat	349..377	CDD:276809	11/27 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910