Protein Alignment Nrd1 and nrdc

DIOPT Version :10

• Sequence 1: NP_572757.2
• Gene: Nrd1 / 32143
• FlyBaseID: FBgn0030344
• Length: 1147
• Species: Drosophila melanogaster
• Sequence 2: XP_031756812.1
• Gene: nrdc / 100489182
• XenbaseID: XB-GENE-970569
• Length: 1060
• Species: Xenopus tropicalis
• Alignment Length: 1099
• Identity: 373/1099 - (33%)
• Similarity: 579/1099 - (52%)
• Gaps: 84/1099 - (7%)

  Fly    44 TDQVKYLDIPD--KSETDKKLYKTLLLGNGLHALIVSDPSPMPHDGFTTSESSSSKSTVSTSSSI 106
            |..:..::.||  ||..|.|.|:.:.|.|||..|:|.|.:.    |...||.|..:.........
 Frog    27 TSSIDGMEDPDIVKSPNDPKKYRYIQLDNGLRVLLVCDLTA----GEIISEYSEDEIEEDDEQGQ 87

  Fly   107 ISRSESTSSTSTDSESSEESSSEEG-----DEKLAACALLIDYGSFAEPTKYQGLAHFLEHMIFM 166
            ....|.....::||::||.|..:.|     :|||:|.||.:..|||::|.:..|:|||||||:||
 Frog    88 EQEQEQEDECASDSQASESSGVDSGNKQGCEEKLSAAALCVGIGSFSDPEELLGMAHFLEHMVFM 152

  Fly   167 GSEKYPKENIFDAHIKKCGGFANANTDCEDTLFYFEVAEKHLDSSLDYFTALMKAPLMKQEAMQR 231
            ||||:|.||.|:..:||.||..||:||.|.|:|.|:|..||....||.:......||:.::|::|
 Frog   153 GSEKFPDENGFEVFLKKYGGSTNASTDAERTIFQFDVQRKHFKQGLDRWAQFFTVPLLIRDAVER 217

  Fly   232 ERSAVDSEFQQILQDDETRRDQLLASLATKGFPHGTFAWGNMKSLK-----ENVDDAELHKILHE 291
            |..|||||||....:|..||..|.||||..|.|...|:|||.::||     :|:|.   |..|.:
 Frog   218 EVEAVDSEFQIGRPNDTNRRQMLFASLAKPGHPMAKFSWGNAQTLKNDPKEKNIDP---HSRLRK 279

  Fly   292 IRKEHYGANRMYVCLQARLPIDELESLVVRHFSGIPHNEVKAPDLSSFNYKDAFKAEFHEQVFFV 356
            ..:..|.||.|.:.:|::..:..||:.|...||.||:|.:..||.|  |..:.|.......::.|
 Frog   280 FYERQYSANYMTLAVQSKETLATLEAWVKEIFSNIPNNGLPKPDYS--NLTEPFNTPDFNLLYRV 342

  Fly   357 KPVENETKLELTWVLPNVRQYYRSKPDQFLSYLLGYEGRGSLCAYLRRRLWALQLIAGIDENGFD 421
            .|::.:..|.::|.:|..:||||.||.::.|:|:|:||:||:.:.||::.||:.|..|....|.:
 Frog   343 VPIKKDHTLTISWAMPPQQQYYRVKPLRYFSWLIGHEGKGSILSLLRKKFWAVSLYGGSSPLGAE 407

  Fly   422 MNSMYSLFNICIYLTDEGFKNLDEVLAATFAYVKLFANCGSMKDVYEEQQRNEETGFRFHAQRPA 486
            .||..::|.|.|.|||.|:::..|||...|.|||:....|..:.::.|.|:.|..||||..|..:
 Frog   408 QNSTCTVFTINITLTDAGYEHFYEVLHIVFQYVKMMQVLGPQERIFREIQQVEANGFRFQEQTES 472

  Fly   487 FDNVQELVLNLKYFPPKDILTGKELYYEYNEEHLKELISHLNEMKFNLMVTSRRKYDDISAYDKT 551
            ..||:::..:::.:...|||||:||.:||..|.:...:.:...:|.|||:.|.   ::....|..
 Frog   473 IKNVEDICEHMQLYAKADILTGEELLFEYKPEIITNALKYFTPLKANLMLLSP---NNEGKCDLV 534

  Fly   552 EEWFGTEYATIPMPEKWRKLWEDSVPL-PELFLPESNKYVTDDFTLHWHSMGRPEVPDSPKLLIK 615
            |::|||:|:...:..||:.||....|| |||.|||.||::..||||........|.|..   ::.
 Frog   535 EKYFGTQYSKEDIDPKWKALWATDFPLIPELHLPEENKFIASDFTLKTSDCPNTEYPVK---VLD 596

  Fly   616 TDTCELWFRQDDKFDLPEAHMAFYFISPMQRQNAKNDAMCSLYEEMVRFHVCEELYPAISAGLSY 680
            |:...||:::|:||.:|:|::.|:.|||..:::.:|..:..::..::...:.|..|.|..|.|.|
 Frog   597 TELGSLWYKKDNKFKIPKAYVRFHLISPEIQKSPENLVLFDIFINILTHTLAESAYEADLAQLEY 661

  Fly   681 SLSTIEKGLLLKVCGYNEKLHLIVEAIAEGMLNVAETLDENMLSAFVKNQRKAFFNALIKPKALN 745
            .:...|.||::.|.|:|.||.|:.|.|.:.:.:...:.||  .....:..:|.:||.|||...|.
 Frog   662 KVEAGEHGLIIGVKGFNHKLPLLFELIIDHLADFTASTDE--FEMITEQLKKIYFNQLIKQTKLG 724

  Fly   746 RDIRLCVLERIRWLMINKYK-CLSSVILEDMREFAHQFPKELYIQSLIQGNYTEESAHNVMNSLL 809
            .||||.:||..||.|:.||: .|..|.|:.|..|...|...||.:.|:|||:|.:.:...:|.::
 Frog   725 PDIRLIILEHGRWSMMQKYETMLKGVTLKRMLSFVKAFKSRLYAEGLVQGNFTCKESVEFLNYVV 789

  Fly   810 SRLNCKQIRERGRFLEDITVKLPVGTSIIRCHALNVQDTNTVITNFYQIGPNTVRVESILDLLMM 874
            .:|....:..|.. :|...|:||....:.:..|||.:|.|:.:|.:||.|...:|..::::||::
 Frog   790 KKLKFSHLESRIP-VEFQVVELPSAHHLCKVKALNKEDANSQVTVYYQSGARNLREYTMMELLVL 853

  Fly   875 FVDEPLFDQLRTKEQLGYHVGATVRLNYGIAGYSIMVNSQETKTTADYVEGRIEVFRAKMLQILR 939
            .::||.||.||||:.|||.|..|.|...||.|:||.|.||.||..:::|:.:||.|.......:.
 Frog   854 HMEEPSFDFLRTKQTLGYQVYPTCRNTSGILGFSITVESQATKYNSEFVDQKIEEFLVLFADKIA 918

  Fly   940 HLPQDEYEHTRDSLIKLKLVADLALSTEMSRNWDEIINESYLFDRRRRQIEVLRTLQKDEIINFV 1004
            .|..:|::....:|||.|...|..|..|:.|||:|::.:.|||:|..|:|..|:|..|:::|::.
 Frog   919 ELTDEEFKIQVKALIKKKECEDTNLGEEVDRNWNEVVTQQYLFERLTREISALKTFAKEDMISWF 983

  Fly  1005 ISIDGDNMRKLSVQVIGHRPAGMPEPLCGEDTAKCASKSDDESESENDDDDDEDEEEEESSEEEE 1069
            .:..|.:.:.|||..:|.   |..||    |.|.|......:|.|
 Frog   984 KAHRGSDRKVLSVHAVGF---GEKEP----DAATCYPAGQPDSSS-------------------- 1021

  Fly  1070 EEEKEKEGLKGEDEDDLFYSLENKLNIVFLPAK--FNNAFIITDIEKFKDDQYVYPQQK 1126
                                   .|.:.||||.  ..:|.:||||..|.....::|..|
 Frog  1022 -----------------------SLCLSFLPATPLMASAVLITDIPAFTAPLKLFPYHK 1057

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrd1	NP_572757.2	Ptr	55..1030	CDD:440648	350/986 (35%)
nrdc	XP_031756812.1	Ptr	38..1054	CDD:440648	368/1083 (34%)