Protein Alignment ATP7 and kdpB

DIOPT Version :10

• Sequence 1: NP_572756.3
• Gene: ATP7 / 32142
• FlyBaseID: FBgn0030343
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_415225.1
• Gene: kdpB / 947450
• ECOCYCID: EG10514
• Length: 682
• Species: Escherichia coli
• Alignment Length: 657
• Identity: 173/657 - (26%)
• Similarity: 279/657 - (42%)
• Gaps: 169/657 - (25%)

  Fly   454 SMVTTISYVYSVAVVIAAVLLEQNSSPLTFFDTPPMLLIFISLGRWL----------EHIAKGKT 508
            |::||   ..|:|:...|:              |...|...::..||          |.:|:|::
E. coli    43 SLLTT---CISIAMASGAM--------------PGNALFSAAISGWLWITVLFANFAEALAEGRS 90

  Fly   509 SEALSKLLSLKAADALLVEISPDFDIISEKVISVDYVQRGDILKVIPGAKVPVDGKVLYGHSSCD 573
            ....:.|..:|..........|.:...::|| ..|.:::|||:.|..|..:|.||:|:.|.:|.|
E. coli    91 KAQANSLKGVKKTAFARKLREPKYGAAADKV-PADQLRKGDIVLVEAGDIIPCDGEVIEGGASVD 154

  Fly   574 ESLITGESMPVAKRKG---SVVIGGSINQNGVLLVEATHTGENTTLAQIVRLVEEAQTSKAPIQQ 635
            ||.|||||.||.:..|   :.|.||:...:..|::|.:.....|.|.:::.:||.||..|.| .:
E. coli   155 ESAITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTP-NE 218

  Fly   636 LADRIAGYFVPFVVVVSSITL---IAWIIIGFSNPNLVPVAMEHKMHMDQNTIIVSYAFKCALSV 697
            :|..|....:..|.::::.||   .||      ..|.|.|           |::|        ::
E. coli   219 IALTILLIALTIVFLLATATLWPFSAW------GGNAVSV-----------TVLV--------AL 258

  Fly   698 LAIACPCALGLATPTAVMVATGTGAIN-----GVLVKGATALENAHKVKTVVFDKTGTITHGTPM 757
            |....|..:|     .::.|.|...::     .|:.....|:|.|..|..::.|||||||.|...
E. coli   259 LVCLIPTTIG-----GLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQ 318

  Fly   758 TSKVTLFVTAQVC---SLARALTIVGAAEQNSEHPIASAIVHFAKDMLNVGATPQAGSFGKSSHF 819
            .|:   |:.||..   :||.|..:...|:   |.|...:||..||...|
E. coli   319 ASE---FIPAQGVDEKTLADAAQLASLAD---ETPEGRSIVILAKQRFN---------------- 361

  Fly   820 QAVPGCGIRVTVSNYEQTLRQACNADRIINYENLHRTHPQGSVPVD-----NGASIEHLLPQRSV 879
                              ||:.       :.::||.|.    ||..     :|.:|::    |.:
E. coli   362 ------------------LRER-------DVQSLHATF----VPFTAQSRMSGINIDN----RMI 393

  Fly   880 RKSMELNNQQLLSDLVLEPEEELLTDQKIIDSPEILVLIGNREWMERNAIEVPLEISDCMTHEER 944
            ||..                         :|:        .|..:|.|....|.::...:....|
E. coli   394 RKGS-------------------------VDA--------IRRHVEANGGHFPTDVDQKVDQVAR 425

  Fly   945 KGHTAVLCALNGQLVCMFAVSDMVKPEAHLAVYTLKRMGIDVVLLTGDNKNTAASIAREVGIRTV 1009
            :|.|.::.....:::.:.|:.|:||.........|::|||..|::||||:.|||:||.|.|:...
E. coli   426 QGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDF 490

  Fly  1010 YAEVLPSHKVAKIQRIQANGIRVAMVGDGVNDSPALAQADVGITIAAGTDVAAEASDIVLMRND- 1073
            .||..|..|:|.|::.||.|..|||.|||.||:||||||||.:.:.:||..|.||.::|.:.::
E. coli   491 LAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNP 555

  Fly  1074 --LLDVV 1078
              |::||
E. coli   556 TKLIEVV 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP7	NP_572756.3	CopZ	11..76	CDD:442020
		HMA	97..159	CDD:238219
		chaper_CopZ_Eh	212..276	CDD:411374
		HMA	287..350	CDD:238219
		P-type_ATPase_Cu-like	376..1130	CDD:319783	173/657 (26%)
kdpB	NP_415225.1	KdpB	3..682	CDD:441818	173/657 (26%)