Protein Alignment ATP7 and PAA2

DIOPT Version :10

• Sequence 1: NP_572756.3
• Gene: ATP7 / 32142
• FlyBaseID: FBgn0030343
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_680181.2
• Gene: PAA2 / 832253
• AraportID: AT5G21930
• Length: 883
• Species: Arabidopsis thaliana
• Alignment Length: 1026
• Identity: 306/1026 - (29%)
• Similarity: 489/1026 - (47%)
• Gaps: 211/1026 - (20%)

  Fly   184 PTPPPPSYAQNGSAVAIPVEQELLTKCFLHIRGMTCASCVAAIEKHCKKIYGLDSILVALLAAKA 248
            |.|||       |::.|...:.|:.:||..:|.       :.|.:||.:.:.|.|..|.:    :
plant     9 PLPPP-------SSLHIRPSKFLVNRCFPRLRR-------SRIRRHCSRPFFLVSNSVEI----S 55

  Fly   249 EVKFNANVVTAENIAKSITELGFPTELIDEPDNGEAEVELEIMGMTCASCVNKIESHVLKIRGVT 313
            ...|.:...:.|:: ||||.        |.|      :.|::.||.|..||.:::|.::....|.
plant    56 TQSFESTESSIESV-KSITS--------DTP------ILLDVSGMMCGGCVARVKSVLMSDDRVA 105

  Fly   314 TASVTLLTKRGKFRY-----ITEETGPRSICEAIEALGFEAKLMTGRDKMAHNYLEHKEEIRKWR 373
            :|.|.:||:....::     :|.:|. .|:.:.:...|||||.......:|.|       ::||:
plant   106 SAVVNMLTETAAVKFKPEVEVTADTA-ESLAKRLTESGFEAKRRVSGMGVAEN-------VKKWK 162

  Fly   374 NAFLVS----LIFGGPCMVAMIYFMLEMSDKGHANMCCLVPGLSMEN---------------LVM 419
            .  :||    |:......||..:.::.:....|.:......|:.:.:               |.:
plant   163 E--MVSKKEDLLVKSRNRVAFAWTLVALCCGSHTSHILHSLGIHIAHGGIWDLLHNSYVKGGLAV 225

  Fly   420 FLLSTPVQFFGGFHFYVQSYRAIKHGTTNMDVLISMVTTISYVYSVAVVIAAVLLEQNSSPLTFF 484
            ..|..|     |........:|....:.||:.|:.:.:..::..|: :.:....||.::|   ||
plant   226 GALLGP-----GRELLFDGIKAFGKRSPNMNSLVGLGSMAAFSISL-ISLVNPELEWDAS---FF 281

  Fly   485 DTPPMLLIFISLGRWLEHIAKGKTSEALSKLLSLKAADALLVEISPDFDIISEKV---------I 540
            |.|.|||.|:.|||.||..||.:.|..:::||||.:..:.||..|.|.:...:.|         :
plant   282 DEPVMLLGFVLLGRSLEERAKLQASTDMNELLSLISTQSRLVITSSDNNTPVDSVLSSDSICINV 346

  Fly   541 SVDYVQRGDILKVIPGAKVPVDGKVLYGHSSCDESLITGESMPVAKRKGSVVIGGSINQNGVLLV 605
            |||.::.||.|.|:||...||||.||.|.|..|||::||||:||.|.:|..|..|:||.:|.|.:
plant   347 SVDDIRVGDSLLVLPGETFPVDGSVLAGRSVVDESMLTGESLPVFKEEGCSVSAGTINWDGPLRI 411

  Fly   606 EATHTGENTTLAQIVRLVEEAQTSKAPIQQLADRIAGYFVPFVVVVSSITLIAWIIIGFSNPNLV 670
            :|:.||.|:|:::|||:||:||.:.||:|:|||.|||.||..::.:|::|...|..:|   .::.
plant   412 KASSTGSNSTISKIVRMVEDAQGNAAPVQRLADAIAGPFVYTIMSLSAMTFAFWYYVG---SHIF 473

  Fly   671 P-VAMEHKMHMDQNTIIVSYAFKCALSVLAIACPCALGLATPTAVMVATGTGAINGVLVKGATAL 734
            | |.:......|.:.:.:|  .|.|:.||.::||||||||||||:::.|..||..|.|::|...|
plant   474 PDVLLNDIAGPDGDALALS--LKLAVDVLVVSCPCALGLATPTAILIGTSLGAKRGYLIRGGDVL 536

  Fly   735 ENAHKVKTVVFDKTGTITHGTPMTSKVTLFVTAQVCSLA----RALTIVGAAEQNSEHPIASAIV 795
            |....:..|..|||||:|.|.|        |.:.|.||.    ..|.:..|.|:.:.||||.|||
plant   537 ERLASIDCVALDKTGTLTEGRP--------VVSGVASLGYEEQEVLKMAAAVEKTATHPIAKAIV 593

  Fly   796 HFAKDMLNVGATPQAGSFGKSSHFQAVPGCGIRVTVSNYEQTLRQACNADRIINYENLHRTHPQG 860
            :.| :.||:......|...:       ||.|          ||.:
plant   594 NEA-ESLNLKTPETRGQLTE-------PGFG----------TLAE-------------------- 620

  Fly   861 SVPVDNGASIEHLLPQRSVRKSMELNNQQLLSDLVLEPEEELLTDQKIIDSPEILVLIGNREW-- 923
                                                            ||..  .|.:|:.||
plant   621 ------------------------------------------------IDGR--FVAVGSLEWVS 635

  Fly   924 ---MERNAIEVPLEISDCMTHE-------ERKGHTAVLCALNGQ-LVCMFAVSDMVKPEAHLAVY 977
               :::|.....:::...:.|:       .|...|.|.....|: ::...|:||.::.:|...|.
plant   636 DRFLKKNDSSDMVKLESLLDHKLSNTSSTSRYSKTVVYVGREGEGIIGAIAISDCLRQDAEFTVA 700

  Fly   978 TLKRMGIDVVLLTGDNKNTAASIAREVGIR---TVYAEVLPSHKVAKIQRIQANGIRVAMVGDGV 1039
            .|:..||..|||:||.:...|::|:.|||:   |.|: :.|..|...|..:|::|.||||||||:
plant   701 RLQEKGIKTVLLSGDREGAVATVAKNVGIKSESTNYS-LSPEKKFEFISNLQSSGHRVAMVGDGI 764

  Fly  1040 NDSPALAQADVGIT--IAAGTDVAAEASDIVLMRNDLLDVVACLDLSRCTVRRIRYNFFFASMYN 1102
            ||:|:||||||||.  |.|..:.|:.|:.::|:||.|..||..|.|::.|:.::..|..:|..||
plant   765 NDAPSLAQADVGIALKIEAQENAASNAASVILVRNKLSHVVDALSLAQATMSKVYQNLAWAIAYN 829

  Fly  1103 LLGIPLASGLFAP-YGFTLLPWMASVAMAASSVSVVCSSLLLKMYRKPTAK 1152
            ::.||:|:|:..| |.|.:.|.::...||.||:.||.:||||::::..|:|
plant   830 VISIPIAAGVLLPQYDFAMTPSLSGGLMALSSIFVVSNSLLLQLHKSETSK 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP7	NP_572756.3	CopZ	11..76	CDD:442020
		HMA	97..159	CDD:238219
		chaper_CopZ_Eh	212..276	CDD:411374	13/63 (21%)
		HMA	287..350	CDD:238219	18/67 (27%)
		P-type_ATPase_Cu-like	376..1130	CDD:319783	246/805 (31%)
PAA2	NP_680181.2	HMA	80..146	CDD:238219	18/66 (27%)
		P-type_ATPase_HM	178..870	CDD:319774	250/802 (31%)