Protein Alignment ATP7 and PAA1

DIOPT Version :10

• Sequence 1: NP_572756.3
• Gene: ATP7 / 32142
• FlyBaseID: FBgn0030343
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_974675.1
• Gene: PAA1 / 829490
• AraportID: AT4G33520
• Length: 949
• Species: Arabidopsis thaliana
• Alignment Length: 920
• Identity: 283/920 - (30%)
• Similarity: 423/920 - (45%)
• Gaps: 193/920 - (20%)

  Fly   288 LEIMGMTCASCVNKIESHVLKIRGVTTASVTLLTKRGKFRYITE-ETGP-------RSICEAIEA 344
            |::.||||..|...::..:.....|.:|||.|.|:......:.| ::.|       .::...:..
plant   152 LDVGGMTCGGCSASVKKILESQPQVASASVNLTTETAIVWPVPEAKSVPDWQKSLGETLANHLTN 216

  Fly   345 LGFEAKLMTGRDKMAHNYLEHKEEIRKWRNAFL--------VSLIFGGPCMVAMIYFMLEM---- 397
            .||::   |.||.:..|:.:..|...|.:.|.|        ||......|:|..:...|.:
plant   217 CGFQS---TPRDLVTENFFKVFETKTKDKQARLKESGRELAVSWALCAVCLVGHLTHFLGVNAPW 278

  Fly   398 -----SDKGHANMCCLV---PGLSMENLVMFLLSTPVQFFGGFHFYVQSYRAIKHGTTNMDVLIS 454
                 |...|.::|.:.   ||   ..||:                 ...:::..|:.||:.|:.
plant   279 IHAIHSTGFHVSLCLITLLGPG---RKLVL-----------------DGIKSLLKGSPNMNTLVG 323

  Fly   455 MVTTISY-VYSVAVVIAAVLLEQNSSPLTFFDTPPMLLIFISLGRWLEHIAKGKTSEALSKLLSL 518
            :....|: |.|:|.:|..:..:      |||:.|.||:.|:.|||.||..||.|.:..::.|||:
plant   324 LGALSSFSVSSLAAMIPKLGWK------TFFEEPVMLIAFVLLGRNLEQRAKIKATSDMTGLLSV 382

  Fly   519 KAADALLVEISPDFDIISEKV-ISVDYVQRGDILKVIPGAKVPVDGKVLYGHSSCDESLITGESM 582
            ..:.|.|:   .|.|:.:..| :..:.:..||::.::||.:||.||.|..|.|:.|||..|||.:
plant   383 LPSKARLL---LDGDLQNSTVEVPCNSLSVGDLVVILPGDRVPADGVVKSGRSTIDESSFTGEPL 444

  Fly   583 PVAKRKGSVVIGGSINQNGVLLVEATHTGENTTLAQIVRLVEEAQTSKAPIQQLADRIAGYFVPF 647
            ||.|..||.|..||||.||.|.||...:|..|.:..|:|||||||:.:||:|||.|::||.|...
plant   445 PVTKESGSQVAAGSINLNGTLTVEVHRSGGETAVGDIIRLVEEAQSREAPVQQLVDKVAGRFTYG 509

  Fly   648 VVVVSSITLIAWIIIGFSNPNLVPVAMEHKMHMDQNTIIVSYAFKCALSVLAIACPCALGLATPT 712
            |:.:|:.|...|.:.|   .:::|.|:.:...|       |.|.:.:.|||.:||||||||||||
plant   510 VMALSAATFTFWNLFG---AHVLPSALHNGSPM-------SLALQLSCSVLVVACPCALGLATPT 564

  Fly   713 AVMVATGTGAINGVLVKGATALENAHKVKTVVFDKTGTITHGTPMTSKVTLFVTAQ-----VCSL 772
            |::|.|..||..|:|::|...||....|.|||||||||:|.|.|:.::|.:....:     ..|.
plant   565 AMLVGTSLGARRGLLLRGGDILEKFSLVDTVVFDKTGTLTKGHPVVTEVIIPENPRHNLNDTWSE 629

  Fly   773 ARALTIVGAAEQNSEHPIASAIVHFAKDMLNVGATPQAGSFGKSSHFQAVPGCGI-------RVT 830
            ...|.:..|.|.|:.||:..|||..|:.........:.|:|.:.      ||.|.       |||
plant   630 VEVLMLAAAVESNTTHPVGKAIVKAARARNCQTMKAEDGTFTEE------PGSGAVAIVNNKRVT 688

  Fly   831 VSNYEQTLRQACNADRIINYENLHRTHPQGSVPVDNGASIEHLLPQRSVRKSMELNNQQLLSDLV 895
            |...|...|.....:.::..|                   ||           |:|||.
plant   689 VGTLEWVKRHGATGNSLLALE-------------------EH-----------EINNQS------ 717

  Fly   896 LEPEEELLTDQKIIDSPEILVLIGNREWMERNAIEVPLEISDCMTHEERKGHTAVLCALNGQLVC 960
                               :|.||                                  ::..|..
plant   718 -------------------VVYIG----------------------------------VDNTLAA 729

  Fly   961 MFAVSDMVKPEAHLAVYTLKRMGIDVVLLTGDNKNTAASIAREVGI--RTVYAEVLPSHKVAKIQ 1023
            :....|.|:.:|...|..|.|.||||.:|:||.:|.|..:|..|||  ..|.|.|.|:.|...|.
plant   730 VIRFEDKVREDAAQVVENLTRQGIDVYMLSGDKRNAANYVASVVGINHERVIAGVKPAEKKNFIN 794

  Fly  1024 RIQANGIRVAMVGDGVNDSPALAQADVGITIAAGTDVAAEASDIVLMRNDLLDVVACLDLSRCTV 1088
            .:|.|...|||||||:||:.|||.::||:.:..|...|:|.|.:|||.|.|..::..::|||.|:
plant   795 ELQKNKKIVAMVGDGINDAAALASSNVGVAMGGGAGAASEVSPVVLMGNRLTQLLDAMELSRQTM 859

  Fly  1089 RRIRYNFFFASMYNLLGIPLASGLFAPY-GFTLLPWMASVAMAASSVSVVCSSLLLKMYR----- 1147
            :.::.|.::|..||::|||:|:|:..|. |..|.|.||...|..||:.|:.:||||: ||
plant   860 KTVKQNLWWAFGYNIVGIPIAAGVLLPLTGTMLTPSMAGALMGVSSLGVMTNSLLLR-YRFFSNR 923

  Fly  1148 -----KPTAK 1152
                 ||..|
plant   924 NDKNVKPEPK 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP7	NP_572756.3	CopZ	11..76	CDD:442020
		HMA	97..159	CDD:238219
		chaper_CopZ_Eh	212..276	CDD:411374
		HMA	287..350	CDD:238219	16/69 (23%)
		P-type_ATPase_Cu-like	376..1130	CDD:319783	247/790 (31%)
PAA1	NP_974675.1	ZntA	150..916	CDD:441819	277/900 (31%)