Protein Alignment ATP7 and JYalpha

DIOPT Version :10

• Sequence 1: NP_572756.3
• Gene: ATP7 / 32142
• FlyBaseID: FBgn0030343
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_001104092.2
• Gene: JYalpha / 5740846
• FlyBaseID: FBgn0267363
• Length: 1009
• Species: Drosophila melanogaster
• Alignment Length: 756
• Identity: 155/756 - (20%)
• Similarity: 275/756 - (36%)
• Gaps: 245/756 - (32%)

  Fly   540 ISVDYVQRGDILKVIPGAKVPVDGKVLYGHS-SCDESLITGESMPVAKRK--------------- 588
            ::.|.:.:|||::|..|.:||.|.::|..|. ..|.|.:||||.|..:..
  Fly   169 VTSDEIVKGDIVEVKFGDRVPADIRILEAHGLKVDNSSLTGESEPQVRSTEFTHENPLETKNLAF 233

  Fly   589 -GSVVIGGSINQNGVLLVEATHTGENTTLAQIVRLVEEAQTSKAPIQQLADRIAGYFVPFVVVVS 652
             .:.|:.|:.  .||::.    ||::|.:.:|..|.......::||    .|....|:.|:.:.:
  Fly   234 FSTNVLEGTC--RGVVIA----TGDSTVMGRIANLAAGLDDVQSPI----SREIQLFIRFITIFA 288

  Fly   653 SITLIAWIIIGFSNPNLVPVAMEHKMHMDQNTIIVSYAFKCA----LSVLAIACPCALGLATPTA 713
            .|..:::..|                     ::.:.|.|..|    :.::....|..| |.|.|.
  Fly   289 IILGLSFFAI---------------------SLTLGYEFIDAVVFLIGIIVANVPEGL-LVTVTV 331

  Fly   714 VMVATGTG-AINGVLVKGATALENAHKVKTVVFDKTGTITHGTPMTSKV---------------- 761
            .:..|... |....|||...|:|......|:..|||||:|......:.:
  Fly   332 CLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWYDQIIVESDTTESFR 396

  Fly   762 ------------TLFVTAQVCSLARALTIVGAAEQNSEHPIASAIVHFAKDMLNVGATPQA---- 810
                        .||:.|.:|:.|.   ..|..:   :.|:      |.|| :|..|:..|
  Fly   397 GSHFKIEDKSFNALFMCAALCNSAE---FKGGQD---DIPV------FKKD-VNGNASEAALLKF 448

  Fly   811 --------GSFGKSSHFQAVPGCGIRVTVSNYEQTLRQACNADRIINYENLHRTHPQGSVPVDNG 867
                    |:| :..|        |::|...:..|.:...:.....:.:.......:|:
  Fly   449 TETIFAGIGAF-RQKH--------IKLTEIPFNSTEKYQVSVHEFNSSDGYFIVEMKGA------ 498

  Fly   868 ASIEHLLPQRSVRKSMELNNQ----QLLSDLVLEPEEELL----TDQKIIDSPEILVLIGNREWM 924
                   |:|.:.:...:..|    :|...|.||.||..|    ..::::...::|:.      |
  Fly   499 -------PERILDRCSTIIIQGLSVELTPTLKLEFEEAYLEMGGMGERVLGFADLLLP------M 550

  Fly   925 ERNAI---------EVPLEISDCMTHEERKGHTAVLCALNGQLVCMFAVSDMVKPEAHLAVYTLK 980
            .:..|         ..|||                    |.:.:.:.::.|..:.....||...:
  Fly   551 SKYPISYEFSADPPNFPLE--------------------NLRFLGLISLIDPPRAAVPDAVAKCR 595

  Fly   981 RMGIDVVLLTGDNKNTAASIAREVGIRT------------------------------------- 1008
            ..|:.|:::|||:..||.:|||.|||.|
  Fly   596 SAGVRVIMVTGDHPITAKAIARSVGIITTPTAEDIAKQRGVTVLDIDSRQATAIVVHGGELREMK 660

  Fly  1009 --------------VYAEVLPSHKVAKIQRIQANGIRVAMVGDGVNDSPALAQADVGITIA-AGT 1058
                          |:|...|..|:..::..|..|..||:.||||||||||.:||:|:.:. :|:
  Fly   661 AEELDAVIYYHNEIVFARTSPQQKLIIVEACQRRGEIVAVTGDGVNDSPALKRADIGVAMGISGS 725

  Fly  1059 DVAAEASDIVLMRNDLLDVVACLDLSRCTVRRIRYNFFFASMYNL-----------LGIPLASGL 1112
            ||:.:|:|::|:.::...:|..::..|.....::.:..:....||           ..||||.|.
  Fly   726 DVSKQAADMILLDDNFASIVVGIEEGRIIFDNLKKSIAYTLTSNLPEIVPFLFFVIFDIPLALGT 790

  Fly  1113 FA----PYGFTLLPWMASVAMAASSVSVVCSSLLLKMYRKP 1149
            .|    ..|..:||   ::::|.....   |.::.:|.|.|
  Fly   791 IAILCIDIGTDMLP---AISLAYEKAE---SDIMARMPRDP 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP7	NP_572756.3	CopZ	11..76	CDD:442020
		HMA	97..159	CDD:238219
		chaper_CopZ_Eh	212..276	CDD:411374
		HMA	287..350	CDD:238219
		P-type_ATPase_Cu-like	376..1130	CDD:319783	150/735 (20%)
JYalpha	NP_001104092.2	P-type_ATPase_Na-K_like	51..1006	CDD:319794	155/756 (21%)