Protein Alignment ATP7 and anne

DIOPT Version :9

• Sequence 1: NP_001259466.1
• Gene: ATP7 / 32142
• FlyBaseID: FBgn0030343
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_001096849.1
• Gene: anne / 317815
• FlyBaseID: FBgn0052000
• Length: 1451
• Species: Drosophila melanogaster
• Alignment Length: 1095
• Identity: 211/1095 - (19%)
• Similarity: 364/1095 - (33%)
• Gaps: 372/1095 - (33%)

  Fly   294 TCASC-VNKIES--------------HVLKIRGVTTASV-TLLTKRGKFRYITEETGPRSICEAI 342
            ||:.| :.:.|.              ||.:|:.:|:::: |||.|.   :...|.|  ...|:.:
  Fly   203 TCSQCSLEEAEQVLVTEDYQGKHKMYHVKQIQVLTSSNLKTLLEKE---QQSIERT--HIECDHV 262

  Fly   343 E-ALGFEAKLMTGRDKMAHN--YLEHKEEIRKWRNAFLVSLIFGGPCMVAMIYFMLEMSDKGHAN 404
            | .|.......:.:.|...:  ....|:.:..|.|                           :.|
  Fly   263 ENVLQLSVHFTSAQFKKCSSIRIFRCKQLVYAWNN---------------------------NTN 300

  Fly   405 MCCLVPGLSMENLVMFLLSTPVQFF---GGFHFYVQSYRAIKHGTTNMDV--------LISMVTT 458
            ....:.||.        |:.|..::   .|...:.|..|.|..|...:.|        |...|..
  Fly   301 RFQRINGLD--------LNIPCSYYHQQRGLPVHEQISRRIVFGDNEITVPLRDFKTLLFLEVLN 357

  Fly   459 ISYVYSVAVVIAAVLLEQNSSPLTFFDTPPMLLIFISLGRWLEHIAKGKTSEALSKLLSLKAADA 523
            ..||:.:..||.....:       ::....::|:....|..:..:...|..:.|.|.: ....:|
  Fly   358 PFYVFQLFSVILWFTYD-------YYYYACVILLMSVFGITVSVLQTKKNQDVLQKTV-YNTGNA 414

  Fly   524 LLVEISPDFDIISEKVISVDYVQR----GDILKVIP--GAKVPVDGKVLYGHSSCDESLITGESM 582
            .:|:         .|.:|.:...|    |||:: ||  |..:..|..::.|:...|||::||||:
  Fly   415 WVVD---------HKGLSKELPTRAIVPGDIIE-IPSSGCTLHCDAILISGNCILDESMLTGESV 469

  Fly   583 PVAKRK---------------------GSVVIGGSINQNGVLLVEATHTGENTTLAQIVRLVEEA 626
            ||.|..                     |:.||......:..:|....:||..|...:::|.:
  Fly   470 PVTKTPLPSKRDMIFDKTEHARHTLFCGTKVIQTRYIGSKKVLAFVINTGNITAKGELIRSI--- 531

  Fly   627 QTSKAPIQQLADRIAGYFVPFVVVVSSI----TLIAWIIIGFSNPNLVPVAMEHKMHMDQNTIIV 687
             ....|:....::.:..|:.|:.:::.:    ||:..|:.| ::|  |.:|:|   .:|..||:|
  Fly   532 -LYPPPVDYKFEQDSYKFIQFLAIIACVGFIYTLVTKILRG-TDP--VKIAVE---SLDLITIVV 589

  Fly   688 SYAFKCALSV-----------LAIACPCALGLATPTAVMVATGTGAINGVLVKGATALENAHKVK 741
            ..|...|::|           ..|.|      .:|.::.||   |:||
  Fly   590 PPALPAAMTVGRFYAQKRLKTSEIFC------ISPRSINVA---GSIN----------------- 628

  Fly   742 TVVFDKTGTITH-GTPMTSKVTLFVTAQVCSLARALTIVGAAEQNSEHPIASA----IVHFAKDM 801
            ...||||||:|. |..|...|....|.|.                 :.|:.|.    ..||...|
  Fly   629 CCCFDKTGTLTEDGLDMWGVVPKSSTNQF-----------------QIPLKSVDRLPFDHFLFGM 676

  Fly   802 LNVGATPQAGSFGKSSHFQAVPGCGIRVTVSN------------YEQT---LRQACNADRIINYE 851
            :...:                      :|:.|            :|.|   |..:.|......|.
  Fly   677 VTCHS----------------------ITILNGRMMGDPLDLKMFESTGWELEDSNNIPDTEKYG 719

  Fly   852 NLHRT---HPQGSV----PVDNGASIEHLLPQRSVRKSMELNNQQLLSDLVLEPEEE-------- 901
            .|:.|   .|:|.:    ..::|:..| :..|.||        ..||:.:.:.|.::
  Fly   720 ILYPTILRQPRGGLSGMAETESGSKNE-IKRQSSV--------DDLLATVGISPSQKNFDHGIVR 775

  Fly   902 ----------------LLTDQKI----IDSPEILVLIGNREWMERNAIEVPLEISDCMTHEERKG 946
                            .|:||..    ..|||:|..:...:       .:|...|..::...:||
  Fly   776 EFPFTSALQRMSVVTRCLSDQVFNVYCKGSPEMLKKLCKPQ-------SLPDNYSQQLSEFAKKG 833

  Fly   947 HTAVLCAL----------------------NGQLVCMFAVSDMVKPEAHLAVYTLKRMGIDVVLL 989
            :..:..|.                      |.:.:....:.:.:||:....:..|....|..:::
  Fly   834 YRIIAIAFKALSHKMNYTKVQRLSREEVENNMEFLGFVILENRLKPDTTKVINALNAAKIRTIMI 898

  Fly   990 TGDNKNTAASIAREVGIRTVYAEVLPSHKVAKIQRIQANGIRVAMVGDGVNDSPALAQADVGITI 1054
            ||||..||.|:||:.||      |.||..|            :.:..|.:.||       ..|..
  Fly   899 TGDNILTAISVARDCGI------VSPSQSV------------ITVHADPIGDS-------ANIQT 938

  Fly  1055 AAGTDVAAEASDIVLMRNDLLDVVACLDLSRCTVRRIRYNFFFASMYNLLGIPLASGLFAP---- 1115
            ..||:...:.|.     :....:...|||...|.|.    :.|.|.:|       |.||.|
  Fly   939 NTGTECNFDNSS-----DKHYKLHYTLDLGSKTSRA----YLFKSCFN-------SNLFDPETPE 987

  Fly  1116 ----YGFTLLPWMASVAMAASSVSVVCSSLLLKMYRKPTAKTLRT-AEYEAQLAAERASGSEDE- 1174
                .|.|:....::.::...|.|....|.|.......:.||:.| ...:|:|..:.   :.||
  Fly   988 FTAQVGKTIFHMESTNSLVNESTSSYAESGLPTSDSLASVKTIDTWTHNDAELGIKH---TPDES 1049

  Fly  1175 ---------LDKLSLHRGLDDLPEKGRMPFKRSSTSLISRIFMHDYGNITSPDAK 1220
                     :|..:.....|..||:..:...|.  |:.:|:         |||.|
  Fly  1050 WRRQECIFAMDGKTWQIVKDYFPEEMEILLTRG--SIYARM---------SPDQK 1093

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP7	NP_001259466.1	HMA	16..78	CDD:238219
		HMA	97..159	CDD:238219
		HMA	214..274	CDD:238219
		ZntA	285..1131	CDD:225127	189/993 (19%)
		HMA	287..350	CDD:238219	17/72 (24%)
		E1-E2_ATPase	489..735	CDD:278548	62/287 (22%)
		COG4087	<984..1085	CDD:226572	26/100 (26%)
anne	NP_001096849.1	P5-ATPase	158..291	CDD:289194	19/92 (21%)
		P-ATPase-V	173..1355	CDD:273738	211/1095 (19%)
		E1-E2_ATPase	381..621	CDD:278548	57/266 (21%)
		Cation_ATPase	<758..813	CDD:289987	8/54 (15%)
		HAD_like	<1087..1137	CDD:304363	5/16 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438599
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930