Protein Alignment ATP7 and CG45062

DIOPT Version :9

• Sequence 1: NP_001259466.1
• Gene: ATP7 / 32142
• FlyBaseID: FBgn0030343
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Alignment Length: 619
• Identity: 115/619 - (18%)
• Similarity: 215/619 - (34%)
• Gaps: 182/619 - (29%)

  Fly   600 NGVLLVEATHTGENTTLAQIVRL-VEEAQTSKAPIQQLADRIAGYFVPFVVVVSSITLIAWIIIG 663
            :|:....|...|.||.:..:..| .:|...|::   |...:...|::..|.:|..|.|  ::..|
  Fly    23 SGIGFAVALACGRNTEVGSMTDLCFKERSRSRS---QKHQKQISYYMLLVAIVCFILL--FLTTG 82

  Fly   664 FSNPNLV------------PVAMEHKMHMDQNTIIVSYAFK-CALSVLAIACPCALGLATPTAVM 715
            |.:.::|            ||.:...::............| |  .|..:...|.|||:|
  Fly    83 FEHGHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQC--HVRNLRATCTLGLST----- 140

  Fly   716 VATGTGAINGVLVKGATALENAHKVKTVVFDKTGTITHGTPMTSKV----------TLFVTAQVC 770
                                      .:|.|..||:|......|::          .|.|:||
  Fly   141 --------------------------VIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLDVSAQ-- 177

  Fly   771 SLARALTIVGAAEQNSEHPIAS---AIVHFAKDM----LNVGATPQAGSFGKSSHFQAVPGCGIR 828
             ..|.:.::.|:...::..|..   .:....|||    |::...    .||    ...:|  .|.
  Fly   178 -SPRFIELIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALL----KFG----LMILP--SID 231

  Fly   829 VTVSNYEQTLRQACNADRIINYENLHRTHPQGSVPVDNGASIEHLLPQRS-----VR-------K 881
            :...::|:...:..|::..:.. .:|||.       |....::.:|..:.     :|       :
  Fly   232 LLRHDHEKVANKHYNSEDKVQV-TVHRTR-------DADGHLKLVLLMKGHCEVVIRRCSTFAIR 288

  Fly   882 SMELNNQQLLSDLVLEPEEELLTDQKIIDSPEILVLIGNREWMERNAIEVPLEISDCMTHEERKG 946
            ..||...:.|.:::|...:.||...:.:.:.....|....|:...:.:...||..:....:....
  Fly   289 DEELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAV 353

  Fly   947 HTAVLCALNGQLVCMFAVSDMVKPEAHLAVYTLKRMGIDVVLLTGDNKNTAASIAREVGI----- 1006
            .|..|     :.:.|.|..:..:.....||...:..||.::::|......|.::|.:|||
  Fly   354 DTYSL-----RFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPS 413

  Fly  1007 -------------------RTVYAEVLPSHKVAKIQRIQAN------------------------ 1028
                               .:.||:..|.|:...|:::..|
  Fly   414 DTFQAVNLKRMPPTAEVVDMSQYADEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRL 478

  Fly  1029 GIRVAMVGDGVNDSPALAQADVGITIAAGTDVAAEAS-DIVLMRNDLLDVVA------------- 1079
            |..|:::|..::|:||:..:.||:. ..|:.|..||| |::|:......:|:
  Fly   479 GAVVSVIGGTLHDTPAMRSSHVGVA-KYGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLK 542

  Fly  1080 -----CLDLSRCTVRRIRYNFFFASMYNLLGIPL 1108
                 ||..:.|.:  :.|.|||     ||||||
  Fly   543 KALAYCLATNICNI--LVYLFFF-----LLGIPL 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP7	NP_001259466.1	HMA	16..78	CDD:238219
		HMA	97..159	CDD:238219
		HMA	214..274	CDD:238219
		ZntA	285..1131	CDD:225127	115/619 (19%)
		HMA	287..350	CDD:238219
		E1-E2_ATPase	489..735	CDD:278548	27/148 (18%)
		COG4087	<984..1085	CDD:226572	31/167 (19%)
CG45062	NP_001286726.1	E1-E2_ATPase	<13..132	CDD:278548	22/115 (19%)
		Cation_ATPase	190..284	CDD:289987	17/111 (15%)
		Cation_ATPase_C	582..777	CDD:295563

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438581
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930