DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p24-1 and tmed1b

DIOPT Version :9

Sequence 1:	NP_001259465.1	Gene:	p24-1 / 32140	FlyBaseID:	FBgn0030341	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_001074109.1	Gene:	tmed1b / 791158	ZFINID:	ZDB-GENE-070112-1112	Length:	226	Species:	Danio rerio

Alignment Length:	210	Identity:	62/210 - (29%)
Similarity:	96/210 - (45%)	Gaps:	20/210 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VALMMHCISA-----VEFTFDLADNAVDCFYEEIKKNSSAYFEFQVSAGGQLDVDVTLKDPQGKV 69
            |.|:...::|     .||||.|...:.:|||:....|.|...|:||.||..:|||.::..|||..
Zfish    15 VTLLFGAVNAFSPADTEFTFLLPAASKECFYQSAVHNGSVEIEYQVIAGAGMDVDFSVVSPQGIH 79

  Fly    70 IYSLEKATFDSHQFVAETTGVYTACFGNQFSAFSHKIVYVDFQV---------GEEPALPGVDEH 125
            :.|..:.:...|.......|.|..||.|.||..|.|:|:  |:|         |.:....|:.|.
Zfish    80 LISEFRRSDGVHMVEPTEEGDYQICFDNTFSRLSEKMVF--FEVILDHPSNDAGADDEWAGLGEP 142

  Fly   126 ATV----LTQMETSSQAIHKGLNDILDAQTHHRLREAQGRKRAEDLNQRVMVWSSLETAAVIVIG 186
            .::    |..::.|.:.:|:.|......||..|..||:.|...||...||..||.:....::.:.
Zfish   143 ESILEYKLDDIKESMETVHRRLERSRQMQTFLRAFEARDRNLLEDNLWRVSFWSCVNLLVLLSVA 207

  Fly   187 LVQIMVLRNFFTDRK 201
            .:|:..||..|.|::
Zfish   208 FIQVYTLRRLFDDKR 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p24-1	NP_001259465.1	EMP24_GP25L	21..197	CDD:279450	57/188 (30%)
tmed1b	NP_001074109.1	EMP24_GP25L	31..218	CDD:279450	57/188 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585520
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1292519at2759
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1790
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.880